Literature DB >> 23393676

Diabetic foot: a continuing challenge.

Sanjeev K Gupta1, Surya K Singh.   

Abstract

Diabetes is rapidly emerging as the new global epidemic. The prevalence of diabetes is expected to double in the next three decades. Diabetic foot (DF) is a major complication of long standing diabetes, accounting for nearly 35% of all hospital admissions in diabetic clinics. It also accounts for nearly 80% of all nontraumatic amputations of the lower limb. Due to its significant morbidity and mortality, DF has a staggering economic impact not only on the individual and his family but also the society. The aetiopathogenesis of DF is multifactorial and is related to peripheral neuropathy leading to the insensate foot with foot deformities, peripheral vascular disease and infection in addition to the reduced immunity seen in these patients. The clinical evaluation of the DF in addition to the detailed examination of foot deformities and the ulcers should focus on identifying loss of protective sensation using simple clinical tests as well as an examination of the vascular integrity by a simple hand held Doppler device. Patients of DF should be managed by a multidisciplinary team which in addition to clinical specialists should also include a podiatrist and trained nursing staff. The basic tenets of treatment include of floading, wound bed preparation using repeated debridement, treating local and systemic infection and to identify and correct vascular impairment if it is present. Once the ulcer has healed, recurrences are common and patient education for foot care is of paramount importance as is an annual examination in a dedicated foot clinic. Once an ulcer develops it should be promptly referred to a specialist unit.

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Mesh:

Year:  2012        PMID: 23393676

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN: 0065-2598            Impact factor:   2.622


  7 in total

Review 1.  Diagnostic and prognostic utility of non-invasive imaging in diabetes management.

Authors:  Cristina Barsanti; Francesca Lenzarini; Claudia Kusmic
Journal:  World J Diabetes       Date:  2015-06-25

Review 2.  Quality Randomized Clinical Trials of Topical Diabetic Foot Ulcer Healing Agents.

Authors:  Laura L Bolton
Journal:  Adv Wound Care (New Rochelle)       Date:  2016-03-01       Impact factor: 4.730

Review 3.  The role of microRNAs in the healing of diabetic ulcers.

Authors:  Golnaz Goodarzi; Mahmood Maniati; Durdi Qujeq
Journal:  Int Wound J       Date:  2019-02-28       Impact factor: 3.315

4.  Categories of foot at risk in patients of diabetes at a tertiary care center: Insights into need for foot care.

Authors:  Shyam Kishore; Ashish D Upadhyay; Viveka P Jyotsna
Journal:  Indian J Endocrinol Metab       Date:  2015 May-Jun

Review 5.  The Role of MicroRNAs in Diabetic Complications-Special Emphasis on Wound Healing.

Authors:  João Moura; Elisabet Børsheim; Eugenia Carvalho
Journal:  Genes (Basel)       Date:  2014-09-29       Impact factor: 4.096

Review 6.  Ozone therapy for treating foot ulcers in people with diabetes.

Authors:  Jian Liu; Peng Zhang; Jing Tian; Lun Li; Jun Li; Jin Hui Tian; KeHu Yang
Journal:  Cochrane Database Syst Rev       Date:  2015-10-27

7.  Evaluation of soluble CD200 levels in type 2 diabetic foot and nephropathic patients: association with disease activity.

Authors:  Hasan Onur Arik; Arzu Didem Yalcin; Betul Celik; Derya Seyman; Gulsum Tetik; Bensu Gursoy; Sukran Kose; Saadet Gumuslu
Journal:  Med Sci Monit       Date:  2014-06-26
  7 in total

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