Literature DB >> 23393372

Abnormal cytology during pregnancy--a retrospective analysis of patients in a dysplasia clinic.

Melanie Henes1, Felix Neis, Katharina Rall, Thomas Iftner, Annette Staebler, Tanja Fehm, Ralf Rothmund.   

Abstract

BACKGROUND: The incidence of abnormal cytological results in pregnant women is as much as 7%. Often there is need to advise pregnant women with an abnormal cervical cytology result and monitor them throughout pregnancy, without endangering the mother or child. PATIENTS AND METHODS: We retrospectively analyzed all pregnant women with an abnormal cervical cytology or condyloma in our dysplasia clinic between 01/2008 and 12/2011. Classification of the cervical cytological results was performed according to the Munich II nomenclature and a biopsy was obtained from most patients. Groups were defined in order to assess regression, persistence and progression. Particular attention was paid to the mode of delivery and the postpartum consultation.
RESULTS: A total of 65 pregnant women were treated in the dysplasia clinic. The reason for referral was Pap IIID in 46.2%, Pap IVa in 40% and Pap III or Pap II with condyloma in 6.2% patients. Only one patient presented with a Pap IVb finding. The pregnancy was continued in all but one cases. Postpartum, a total of 40% of cases, were in remission. A partial remission occurred in 4.6%. Persistence of the abnormalities was observed in 26.2%. Progression was documented in 3% and 71.1% were able to have a vaginal delivery. A caesarean section was performed in 22.2%. A total of 4.4% suffered a miscarriage, which was not caused by the colposcopy. DISCUSSION: The distinctive feature of the present study is the high number of follow-up examinations, which showed that even women with highly dysplastic changes in pregnancy, who are regularly monitored can be advised to continue pregnancy. Vaginal delivery is possible in most cases.

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Year:  2013        PMID: 23393372

Source DB:  PubMed          Journal:  Anticancer Res        ISSN: 0250-7005            Impact factor:   2.480


  2 in total

1.  Characterization and clinical management of abnormal cytology findings in pregnant women: a retrospective analysis.

Authors:  Rosa Freudenreich; Martin Weiss; Tobias Engler; Felix Neis; Melanie Henes
Journal:  Arch Gynecol Obstet       Date:  2022-08-17       Impact factor: 2.493

2.  Current status of cervical cytology during pregnancy in Japan.

Authors:  Shunji Suzuki; Eijiro Hayata; Shin-Ichi Hoshi; Akihiko Sekizawa; Yoko Sagara; Masanobu Tanaka; Katsuyuki Kinoshita; Tadaichi Kitamura
Journal:  PLoS One       Date:  2021-01-07       Impact factor: 3.752

  2 in total

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