İrfan Taşoğlu1, Doğan Sert2, Necmettin Colak3, Alper Uzun4, Murat Songur2, Ata Ecevit2. 1. Department of Cardiovascular Surgery, Turkiye Yuksek Ihtisas Heart-Education and Research Hospital, Ankara, Turkey irfantasoglu@yahoo.com. 2. Department of Cardiovascular Surgery, Turkiye Yuksek Ihtisas Heart-Education and Research Hospital, Ankara, Turkey. 3. Department of Cardiology, Ankara Education and Research Hospital, Ankara, Turkey. 4. Department of Cardiovascular Surgery, Fatih Unıversty Medical Faculty, Ankara, Turkey.
Abstract
BACKGROUND: The objective of this study was to evaluate whether admission neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) might reflect amputation in patients with critical limb ischemia (CLI) who could not get surgical or radiological (percutaneous transluminal angioplasty) revascularization. METHODS: A total of 104 patients with nonreconstructable CLI over a 5-year period were collected prospectively. RESULTS: Admission NLR levels of ≥3.2 and a PLR of ≥160 were found to represent the optimal cutoff values to risk stratification of patients. If both levels were elevated, patients had a median overall limb survival of 22 months. For cases where both levels were less than the cutoff values, the median overall limb survival time was not reached but was greater than 60 months. CONCLUSIONS: Admission NLR and PLR both merit further evaluation as prognostic indices in patients with CLI.
BACKGROUND: The objective of this study was to evaluate whether admission neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) might reflect amputation in patients with critical limb ischemia (CLI) who could not get surgical or radiological (percutaneous transluminal angioplasty) revascularization. METHODS: A total of 104 patients with nonreconstructable CLI over a 5-year period were collected prospectively. RESULTS: Admission NLR levels of ≥3.2 and a PLR of ≥160 were found to represent the optimal cutoff values to risk stratification of patients. If both levels were elevated, patients had a median overall limb survival of 22 months. For cases where both levels were less than the cutoff values, the median overall limb survival time was not reached but was greater than 60 months. CONCLUSIONS: Admission NLR and PLR both merit further evaluation as prognostic indices in patients with CLI.
Authors: Thomas Gary; Martin Pichler; Klara Belaj; Franz Hafner; Armin Gerger; Harald Froehlich; Philipp Eller; Peter Rief; Gerald Hackl; Ernst Pilger; Marianne Brodmann Journal: PLoS One Date: 2013-07-02 Impact factor: 3.240
Authors: Ali Ugur Uslu; Koksal Deveci; Serdal Korkmaz; Bahattin Aydin; Soner Senel; Enver Sancakdar; Mehmet Sencan Journal: Biomed Res Int Date: 2013-06-20 Impact factor: 3.411