| Literature DB >> 23392615 |
Sangram S Kale1, Gowri Priya, Amol S Kotmale, Rupesh L Gawade, Vedavati G Puranik, P R Rajamohanan, Gangadhar J Sanjayan.
Abstract
Orthanilic acid (2-aminobenzenesulfonic acid, (S)Ant), an aromatic β-amino acid, has been shown to be highly useful in inducing a folded conformation in peptides. When incorporated into peptide sequences (Xaa-(S)Ant-Yaa), this rigid aromatic β-amino acid strongly imparts a reverse-turn conformation to the peptide backbone, featuring robust 11-membered-ring hydrogen-bonding.Entities:
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Year: 2013 PMID： 23392615 DOI： 10.1039/c3cc40522b
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222