Literature DB >> 23391807

Distance of residence in 1984 may be used as exposure surrogate for the Bhopal disaster.

V Ramana Dhara, Sushma Acquilla.   

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Year:  2012        PMID: 23391807      PMCID: PMC3612314     

Source DB:  PubMed          Journal:  Indian J Med Res        ISSN: 0971-5916            Impact factor:   2.375


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Sir, We read with interest De's conclusions1 that the lung function impairments in the Bhopal population were associated with gas exposure, lower socio-economic status, and smoking. Prior studies have also shown that poorer people living in kuccha houses sustained greater exposure to the gas because of proximity of residence to the Union Carbide plant2. However, the high prevalence of tobacco smokers/ex-smokers in the exposed group is a major confounder which may also account for the study findings. An exposure-response analysis may have helped determine whether gas exposure is truly associated with pulmonary impairment but the author did not attempt such an analysis because of possible recall bias. We suggest that using distance of individual in the residence at the time of gas release in 1984 will serve as a surrogate measure of exposure. Such an approach was successfully used in the ten-year follow up community survey conducted by the International Medical Commission on Bhopal (IMCB)34 and may help determine if the association of gas exposure with respiratory impairment is truly present in this hospital-based study.
  4 in total

1.  Respiratory morbidity 10 years after the Union Carbide gas leak at Bhopal: a cross sectional survey. The International Medical Commission on Bhopal.

Authors:  P Cullinan; S Acquilla; V R Dhara
Journal:  BMJ       Date:  1997-02-01

2.  Long term morbidity in survivors of the 1984 Bhopal gas leak.

Authors:  P Cullinan; S D Acquilla; V R Dhara
Journal:  Natl Med J India       Date:  1996 Jan-Feb       Impact factor: 0.537

3.  Retrospective analysis of lung function abnormalities of Bhopal gas tragedy affected population.

Authors:  Sajal De
Journal:  Indian J Med Res       Date:  2012       Impact factor: 2.375

4.  Personal exposure and long-term health effects in survivors of the union carbide disaster at bhopal.

Authors:  V Ramana Dhara; Rosaline Dhara; Sushma D Acquilla; Paul Cullinan
Journal:  Environ Health Perspect       Date:  2002-05       Impact factor: 9.031

  4 in total
  2 in total

1.  Spectrum of health condition in methyl isocyanate (MIC)-exposed survivors measured after 30 years of disaster.

Authors:  Bani Bandana Ganguly; Shouvik Mandal; Nitin N Kadam
Journal:  Environ Sci Pollut Res Int       Date:  2017-12-05       Impact factor: 4.223

2.  Regarding distance of residence in 1984 may be used as exposure surrogate for the Bhopal disaster - further observations on post-disaster epidemiology.

Authors:  V Ramana Dhara; Sushma Acquilla
Journal:  Indian J Med Res       Date:  2013       Impact factor: 2.375

  2 in total

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