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Literature DB >> 233908

Antiviral protection by virus-immune cytotoxic T cells: infected target cells are lysed before infectious virus progeny is assembled.

Abstract

Virus-immune cytotoxic T cells can inhibit effectively growth of vaccinia virus in acutely infected target cells in vitro by destroying infected target cells before infectious virus progeny is assembled. Together with the fact that virus-specific T cells are demonstrable after 3 days, very early during infection, and with strong circumstantial evidence from adoptive transfer models in vivo, these data suggest that in some virus infections T cells may in fact act cytolytically in vivo to prevent virus growth and spread and be an important early antiviral effector mechanism.

Entities: Disease

Mesh：

Year: 1977 PMID： 233908 PMCID： PMC2180721 DOI： 10.1084/jem.145.3.644

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

11 in total

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Authors: E Earley; P H Peralta; K M Johnson
Journal: Proc Soc Exp Biol Med Date: 1967-07

2. Changes in the surface of virus-induced cells recognized by cytotoxic T cells. I. Minimal requirements for lysis of ectromelia-infected P-815 cells.

Authors: G I Ada; D C Jackson; R V Blanden; R T Hla; N A Bowern
Journal: Scand J Immunol Date: 1976 Impact factor: 3.487

3. Cell-mediated cytotoxicity to trinitrophenyl-modified syngeneic lymphocytes.

Authors: G M Shearer
Journal: Eur J Immunol Date: 1974-08 Impact factor: 5.532

4. Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system.

Authors: R M Zinkernagel; P C Doherty
Journal: Nature Date: 1974-04-19 Impact factor: 49.962

5. Cell-medicated cytotoxicity against ectromelia virus-infected target cells. III. Role of the H-2 gene complex.

Authors: I D Gardner; N A Bowern; R V Blanden
Journal: Eur J Immunol Date: 1975-02 Impact factor: 5.532

6. Cells that express viral antigens but lack H-2 determinants are not lysed by immune thymus-derived lymphocytes but are lysed by other antiviral immune attack mechanisms.

Authors: R M Zinkernagel; M B Oldstone
Journal: Proc Natl Acad Sci U S A Date: 1976-10 Impact factor: 11.205

7. Target cell-dependent T cell-mediated lysis of vaccinia virus-infected cells.

Authors: U Koszinowski; R Thomssen
Journal: Eur J Immunol Date: 1975-04 Impact factor: 5.532

8. H-2 compatibility requirement for virus-specific T cell-mediated effector functions in vivo. I. Specificity of T cells conferring antiviral protection against lymphocytic choriomeningitis virus is associated with H-2K and H-2D.

Authors: R M Zinkernagel; R M Welsh
Journal: J Immunol Date: 1976-11 Impact factor: 5.422

9. H-2 restriction of virus-specific cytotoxicity across the H-2 barrier. Separate effector T-cell specificities are associated with self-H-2 and with the tolerated allogeneic H-2 in chimeras.

Authors: R M Zinkernagel
Journal: J Exp Med Date: 1976-10-01 Impact factor: 14.307

10. A single genetic element in H-2K affects mouse T-cell antiviral function in poxvirus infection.

Authors: U Kees; R V Blanden
Journal: J Exp Med Date: 1976-02-01 Impact factor: 14.307

51 in total

Review 1. Immunostimulatory DNA sequences help to eradicate intracellular pathogens.

Authors: H Wagner; H Häcker; G B Lipford
Journal: Springer Semin Immunopathol Date: 2000

2. Fate of herpes simplex virus in lymphocytes from inflammatory joint effusions. ii. Mechanisms of non-permissiveness.

Authors: D J Appleford; A M Denman
Journal: Ann Rheum Dis Date: 1979-10 Impact factor: 19.103

3. Lysis of HIV-1-infected cells and inhibition of viral replication by universal receptor T cells.

Authors: O O Yang; A C Tran; S A Kalams; R P Johnson; M R Roberts; B D Walker
Journal: Proc Natl Acad Sci U S A Date: 1997-10-14 Impact factor: 11.205

4. Virus-specific CD4+ and CD8+ cytotoxic T-cell responses and long-term T-cell memory in individuals vaccinated against polio.

Authors: Rahnuma Wahid; Martin J Cannon; Marie Chow
Journal: J Virol Date: 2005-05 Impact factor: 5.103

5. Epitope-dependent avidity thresholds for cytotoxic T-lymphocyte clearance of virus-infected cells.

Authors: Michael S Bennett; Hwee L Ng; Mirabelle Dagarag; Ayub Ali; Otto O Yang
Journal: J Virol Date: 2007-02-28 Impact factor: 5.103

Review 6. Initiation of primary anti-vaccinia virus immunity in vivo.

Authors: Matthew A Fischer; Christopher C Norbury
Journal: Immunol Res Date: 2007 Impact factor: 2.829

7. A unique variant of lymphocytic choriomeningitis virus that induces pheromone binding protein MUP: Critical role for CTL.

Authors: Brian C Ware; Brian M Sullivan; Stephanie LaVergne; Brett S Marro; Toru Egashira; Kevin P Campbell; John Elder; Michael B A Oldstone
Journal: Proc Natl Acad Sci U S A Date: 2019-08-19 Impact factor: 11.205

8. Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy.

Authors: M A Alexander-Miller; G R Leggatt; J A Berzofsky
Journal: Proc Natl Acad Sci U S A Date: 1996-04-30 Impact factor: 11.205

9. Analysis of CD8⁺ T cell response during the 2013-2016 Ebola epidemic in West Africa.

Authors: Saori Sakabe; Brian M Sullivan; Jessica N Hartnett; Refugio Robles-Sikisaka; Karthik Gangavarapu; Beatrice Cubitt; Brian C Ware; Dylan Kotliar; Luis M Branco; Augustine Goba; Mambu Momoh; John Demby Sandi; Lansana Kanneh; Donald S Grant; Robert F Garry; Kristian G Andersen; Juan Carlos de la Torre; Pardis C Sabeti; John S Schieffelin; Michael B A Oldstone
Journal: Proc Natl Acad Sci U S A Date: 2018-07-23 Impact factor: 11.205

10. Synthesis of an HIV-1 Tat transduction domain-rotavirus enterotoxin fusion protein in transgenic potato.

Authors: T-G Kim; W H R Langridge
Journal: Plant Cell Rep Date: 2003-10-10 Impact factor: 4.570