Literature DB >> 23390

Determination of the metabolites of bezitramide in urine. I. Acidic metabolite.

H H van Rooy, M Kok, E Modderman, C S Agnie.   

Abstract

Two methylation methods are compared in relation to the determination of low levels (less than microgram/ml) of the acidic metabolite of bezitramide in human urine. It was necessary to use alkali flame ionisation detector, which specifically detects nitrogen-containing compounds. Several difficulties associated with the use of this detector are described.

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Year:  1978        PMID: 23390     DOI: 10.1016/s0021-9673(00)85302-9

Source DB:  PubMed          Journal:  J Chromatogr


  1 in total

1.  Pharmacokinetics of the oral narcotic analgesic bezitramide and preliminary observations on its effect on experimentally induced pain.

Authors:  D K Meijer; G Hovinga; A Versluis; J Bröring; K van Aken; F Moolenaar; H Wesseling
Journal:  Eur J Clin Pharmacol       Date:  1984       Impact factor: 2.953

  1 in total

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