Literature DB >> 23386948

Hemorrhagic cardioembolic stroke secondary to a left ventricular thrombus: a therapeutic dilemma.

Khalil Al-Farsi1, Aftab A Siddiqui, Yasser W Sharef, Ali K Al-Belushi, Hakeem Al-Hashim, Mohammed Al-Ghailani, William J Johnston.   

Abstract

Cardiogenic embolism is a major cause of stroke and often leads to significant morbidity and mortality. Despite the recent advances in our understanding of the pathophysiology of stroke and its risk factors, diagnosis and therapy; some case scenarios still present a real challenge for the treating physicians. We report a case of a 50 year old male patient presenting with multi-territory cerebral infarctions due to a left ventricular mobile thrombus complicated with hemorrhagic transformation at the time of presentation. Gradual introduction of anticoagulation coupled with a multidisciplinary team approach advocating careful daily clinical assessment of the patient and regular echocardiographic and neuroimaging studies have resulted in a better management and achievement of therapeutic goals.

Entities:  

Keywords:  Cardioembolism; Echocardiography; Hemorrhagic transformation; Mobile thrombus; Multidisciplinary approach; Stroke

Year:  2013        PMID: 23386948      PMCID: PMC3562974          DOI: 10.5001/omj.2013.13

Source DB:  PubMed          Journal:  Oman Med J        ISSN: 1999-768X


  33 in total

1.  Efficacy and safety of anticoagulant treatment in acute cardioembolic stroke: a meta-analysis of randomized controlled trials.

Authors:  Maurizio Paciaroni; Giancarlo Agnelli; Sara Micheli; Valeria Caso
Journal:  Stroke       Date:  2007-01-04       Impact factor: 7.914

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3.  Safety of discontinuation of anticoagulation in patients with intracranial hemorrhage at high thromboembolic risk.

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Journal:  Arch Neurol       Date:  1989-07

Review 5.  Considering the role of heparin and low-molecular-weight heparins in acute ischemic stroke.

Authors:  Majaz Moonis; Marc Fisher
Journal:  Stroke       Date:  2002-07       Impact factor: 7.914

6.  Evaluation of the risk of immediate anticoagulant treatment in patients with embolic stroke of cardiac origin.

Authors:  J Lodder; P J van der Lugt
Journal:  Stroke       Date:  1983 Jan-Feb       Impact factor: 7.914

7.  Detection of left ventricular thrombus by two-dimensional echocardiography: sensitivity, specificity, and causes of uncertainty.

Authors:  J R Stratton; G W Lighty; A S Pearlman; J L Ritchie
Journal:  Circulation       Date:  1982-07       Impact factor: 29.690

8.  Hemorrhagic transformation in cardioembolic cerebral infarction.

Authors:  C R Hornig; T Bauer; C Simon; S Trittmacher; W Dorndorf
Journal:  Stroke       Date:  1993-03       Impact factor: 7.914

9.  The Harvard Cooperative Stroke Registry: a prospective registry.

Authors:  J P Mohr; L R Caplan; J W Melski; R J Goldstein; G W Duncan; J P Kistler; M S Pessin; H L Bleich
Journal:  Neurology       Date:  1978-08       Impact factor: 9.910

Review 10.  Management of cerebral embolism of cardiac origin.

Authors:  J D Easton; D G Sherman
Journal:  Stroke       Date:  1980 Sep-Oct       Impact factor: 7.914

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  3 in total

1.  Multiple foci of infarction secondary to giant left ventricular thrombus in a patient with takotsubo cardiomyopathy.

Authors:  Murat Celik; Emre Yalcinkaya; Uygar Cagdas Yuksel; Turgay Celik; Atila Iyisoy
Journal:  Oman Med J       Date:  2013-07

2.  Feasibility of the Big 5-Jena eCS Protocol : First Experience Implementing a New Extended CT Protocol in the Initial Diagnostics of Ischemic Stroke.

Authors:  Moisés F Molina-Fuentes; Rotraud Neumann; Wilhelm Behringer; Marcus Franz; P Christian Schulze; Otto W Witte; Albrecht Günther; Carsten Klingner; Lukas Lehmkuhl; Beatrice Steiniger; Ulf Teichgräber; J E Rod; Thomas E Mayer
Journal:  Clin Neuroradiol       Date:  2021-08-11       Impact factor: 3.649

Review 3.  Takotsubo cardiomyopathy complicated with apical thrombus formation on first day of the illness: a case report and literature review.

Authors:  H M M T B Herath; S P Pahalagamage; Laura C Lindsay; S Vinothan; Sampath Withanawasam; Vajira Senarathne; Milinda Withana
Journal:  BMC Cardiovasc Disord       Date:  2017-07-03       Impact factor: 2.298

  3 in total

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