Literature DB >> 23386510

[Pertussis in a 4-month-old infant with unrecognized cystic fibrosis].

Lukáš Homola1, Alena Holčíková, Eliška Zárošská, Lenka Krbková, Renata Gaillyová, Markéta Hanslianová, Pavla Cižmářová.   

Abstract

We present a case report of a small boy with cystic fibrosis complicated by pertussis and pneumothorax. The child had not been vaccinated against Bordetella pertussis due to the failure to thrive and was infected with the bacterium at the age of 4 months. The course of the disease was severe, with respiratory distress and spontaneous pneumothorax. The diagnosis of pertussis was serologically confirmed. A suspicion for cystic fibrosis increased after an unusually prolonged course of the disease and a history of the failure to thrive. A comprehensive diagnostic procedure revealed Pseudomonas aeruginosa respiratory infection, anemia, pancreatic insufficiency, a positive sweat test and the presence of two CFTR gene mutations. The patient, treated with comprehensive cystic fibrosis therapy, recovered from acute respiratory illness and started to thrive soon.

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Year:  2012        PMID: 23386510

Source DB:  PubMed          Journal:  Klin Mikrobiol Infekc Lek        ISSN: 1211-264X


  2 in total

1.  Clinical presentation of air leak in an infant with undiagnosed cystic fibrosis: a case report.

Authors:  Mohammed M Al-Balawi; Khalid Al-Mobaireek; Wadha Alotaibi; Abdullah Al-Shamrani; Khalid S Ahmad; Suhail Al-Saleh
Journal:  J Med Case Rep       Date:  2015-07-11

Review 2.  Conquering the host: Bordetella spp. and Pseudomonas aeruginosa molecular regulators in lung infection.

Authors:  Alina M Holban; Courtney M Gregoire; Monica C Gestal
Journal:  Front Microbiol       Date:  2022-09-26       Impact factor: 6.064

  2 in total

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