Literature DB >> 23386213

Pt(II) compounds interplay with Cu(II) and Zn(II) coordination to the amyloid-β peptide has metal specific consequences on deleterious processes associated to Alzheimer's disease.

Fabrice Collin1, Isabelle Sasaki, Hélène Eury, Peter Faller, Christelle Hureau.   

Abstract

Five Pt(II) complexes were tested for their ability to interfere in Cu(II) or Zn(II) coordination to the Aβ peptide. Two of them induce modifications of the Cu(II) sphere but not the associated Cu(Aβ) ROS production. In contrast, they do completely preclude Zn induced Aβ aggregation.

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Year:  2013        PMID: 23386213     DOI: 10.1039/c3cc38537j

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  9 in total

1.  Ligand field molecular dynamics simulation of Pt(II)-phenanthroline binding to N-terminal fragment of amyloid-β peptide.

Authors:  Matthew Turner; Shaun T Mutter; Robert J Deeth; James A Platts
Journal:  PLoS One       Date:  2018-03-06       Impact factor: 3.240

2.  Modulation of amyloid-β aggregation by histidine-coordinating Cobalt(III) Schiff base complexes.

Authors:  Marie C Heffern; Pauline T Velasco; Lauren M Matosziuk; Joseph L Coomes; Constantine Karras; Mark A Ratner; William L Klein; Amanda L Eckermann; Thomas J Meade
Journal:  Chembiochem       Date:  2014-06-24       Impact factor: 3.164

3.  Zn(II) ions substantially perturb Cu(II) ion coordination in amyloid-β at physiological pH.

Authors:  K Ishara Silva; Sunil Saxena
Journal:  J Phys Chem B       Date:  2013-07-31       Impact factor: 2.991

4.  Platinum(II) O,S Complexes Inhibit the Aggregation of Amyloid Model Systems.

Authors:  Daniele Florio; Anna Maria Malfitano; Sarah Di Somma; Carolin Mügge; Wolfgang Weigand; Giarita Ferraro; Ilaria Iacobucci; Maria Monti; Giancarlo Morelli; Antonello Merlino; Daniela Marasco
Journal:  Int J Mol Sci       Date:  2019-02-14       Impact factor: 5.923

5.  A catalytic antioxidant for limiting amyloid-beta peptide aggregation and reactive oxygen species generation.

Authors:  Luiza M F Gomes; Atif Mahammed; Kathleen E Prosser; Jason R Smith; Michael A Silverman; Charles J Walsby; Zeev Gross; Tim Storr
Journal:  Chem Sci       Date:  2018-12-03       Impact factor: 9.825

6.  Modification of Aβ Peptide Aggregation via Covalent Binding of a Series of Ru(III) Complexes.

Authors:  Luiza M F Gomes; Janaina C Bataglioli; Allison J Jussila; Jason R Smith; Charles J Walsby; Tim Storr
Journal:  Front Chem       Date:  2019-12-03       Impact factor: 5.221

7.  A Metallo Pro-Drug to Target CuII in the Context of Alzheimer's Disease.

Authors:  Amandine Conte-Daban; Vinita Ambike; Régis Guillot; Nicolas Delsuc; Clotilde Policar; Christelle Hureau
Journal:  Chemistry       Date:  2018-02-16       Impact factor: 5.236

8.  Inhibition of Beta-Amyloid Fibrillation by Luminescent Iridium(III) Complex Probes.

Authors:  Lihua Lu; Hai-Jing Zhong; Modi Wang; See-Lok Ho; Hung-Wing Li; Chung-Hang Leung; Dik-Lung Ma
Journal:  Sci Rep       Date:  2015-09-30       Impact factor: 4.379

9.  A Comparative Study of the Effects of Platinum (II) Complexes on β-Amyloid Aggregation: Potential Neurodrug Applications.

Authors:  Sara La Manna; Daniele Florio; Ilaria Iacobucci; Fabiana Napolitano; Ilaria De Benedictis; Anna Maria Malfitano; Maria Monti; Mauro Ravera; Elisabetta Gabano; Daniela Marasco
Journal:  Int J Mol Sci       Date:  2021-03-16       Impact factor: 5.923

  9 in total

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