Literature DB >> 23382743

Pediatric HIV/AIDS in sub-Saharan Africa: emerging issues and way forward.

A C Ubesie1.   

Abstract

BACKGROUND: Sub-Saharan Africa has the largest burden of pediatric HIV in the world. Global target has been set for eradication of pediatric HIV by 2015 but there are still so many complex issues facing HIV infected and affected children in the sub-continent.
OBJECTIVE: To review the current and emerging challenges facing pediatric HIV care in sub-Saharan Africa; and proffer solutions that could help in tackling these challenges.
METHOD: A Medline literature search of recent publications was performed to identify articles on "pediatric HIV", "HIV and children", "HIV and infants", "HIV and adolescents" in sub-Saharan Africa. RESULT: There are a number of challenges and emerging complex issues facing children infected and affected by HIV in sub-Saharan Africa. These include late presentation, limited access to pediatric HIV services, delayed diagnosis, infant feeding choices, malnutrition, limited and complex drug regimen, disclosure, treatment failure and reproductive health concerns. A holistic cost effective preventive, diagnostic and treatment strategies are required in order to eliminate pediatric HIV in SSA.
CONCLUSION: HIV infected children and their families in sub-Saharan Africa face myriad of complex medical and psychosocial issues. A holistic health promotional approach is being advocated as the required step for eradication of pediatric HIV in Africa.

Entities:  

Keywords:  Challenges; Pediatric HIV; sub-Saharan Africa

Mesh:

Substances:

Year:  2012        PMID: 23382743      PMCID: PMC3557677          DOI: 10.4314/ahs.v12i3.8

Source DB:  PubMed          Journal:  Afr Health Sci        ISSN: 1680-6905            Impact factor:   0.927


  36 in total

1.  Recent advances in prevention of mother to child (PMTCT) of HIV.

Authors:  Philipa Musoke
Journal:  Afr Health Sci       Date:  2004-12       Impact factor: 0.927

2.  Uganda edges closer to AIDS treatment for all.

Authors:  Musinguzi Bamuturaki
Journal:  Bull World Health Organ       Date:  2008-06       Impact factor: 9.408

3.  The performance of 5 rapid HIV tests using whole blood in infants and children: selecting a test to achieve the clinical objective.

Authors:  Gayle G Sherman; Rivka R Lilian; Ashraf H Coovadia
Journal:  Pediatr Infect Dis J       Date:  2012-03       Impact factor: 2.129

4.  Sociocultural and epidemiological aspects of HIV/AIDS in Mozambique.

Authors:  Carolyn M Audet; Janeen Burlison; Troy D Moon; Mohsin Sidat; Alfredo E Vergara; Sten H Vermund
Journal:  BMC Int Health Hum Rights       Date:  2010-06-08

5.  Perinatal outcomes, including mother-to-child transmission of HIV, and child mortality and their association with maternal vitamin D status in Tanzania.

Authors:  Saurabh Mehta; David J Hunter; Ferdinand M Mugusi; Donna Spiegelman; Karim P Manji; Edward L Giovannucci; Ellen Hertzmark; Gernard I Msamanga; Wafaie W Fawzi
Journal:  J Infect Dis       Date:  2009-10-01       Impact factor: 5.226

6.  Milking the cow: young women's construction of identity and risk in age-disparate transactional sexual relationships in Maputo, Mozambique.

Authors:  K Hawkins; N Price; F Mussa
Journal:  Glob Public Health       Date:  2009

7.  Early antiretroviral therapy and mortality among HIV-infected infants.

Authors:  Avy Violari; Mark F Cotton; Diana M Gibb; Abdel G Babiker; Jan Steyn; Shabir A Madhi; Patrick Jean-Philippe; James A McIntyre
Journal:  N Engl J Med       Date:  2008-11-20       Impact factor: 91.245

8.  Meeting the challenges of the Ottawa Charter: comparing South African responses to AIDS and tobacco control.

Authors:  M Taylor; A Meyer-Weitz; C C Jinabhai; R Sathiparsad
Journal:  Health Promot Int       Date:  2009-06-13       Impact factor: 2.483

9.  Paediatric HIV and elimination of mother-to-child transmission of HIV in the ASEAN region: a call to action.

Authors:  Naoko Ishikawa; Kyoko Ishigaki; Massimo N Ghidinelli; Kazuko Ikeda; Miwako Honda; Hideki Miyamoto; Kazuhiro Kakimoto; Shinichi Oka
Journal:  AIDS Care       Date:  2011-04

10.  Barriers to Initiation of Pediatric HIV Treatment in Uganda: A Mixed-Method Study.

Authors:  T Sonia Boender; Kim C E Sigaloff; Joshua Kayiwa; Victor Musiime; Job C J Calis; Raph L Hamers; Lillian Katumba Nakatudde; Elizabeth Khauda; Andrew Mukuye; James Ditai; Sibyl P Geelen; Peter Mugyenyi; Tobias F Rinke de Wit; Cissy Kityo
Journal:  AIDS Res Treat       Date:  2012-02-06
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  11 in total

1.  A qualitative analysis of the barriers to antiretroviral therapy initiation among children 2 to 18 months of age in Swaziland.

Authors:  Charisse V Ahmed; Pauline Jolly; Luz Padilla; Musa Malinga; Chantal Harris; Nobuhle Mthethwa; Inessa Ba; Amy Styles; Sarah Perry; Raina Brooks; Florence Naluyinda-Kitabire; Makhosini Mamba; Peter Preko
Journal:  Afr J AIDS Res       Date:  2017-12       Impact factor: 1.300

2.  Factors associated with the risk of HIV infection among HIV-exposed infants in Malawi: 2013-2020.

Authors:  Wingston Felix Ng'ambi; Fatma Aziza Merzouki; Janne Estill; Erol Orel; Tiwonge Chimpandule; Rose Nyirenda; Olivia Keiser
Journal:  BMJ Paediatr Open       Date:  2022-01

3.  Clinical characteristics and outcomes after new-onset seizure among Zambian children with HIV during the antiretroviral therapy era.

Authors:  Mathura Ravishankar; Ifunanya Dallah; Manoj Mathews; Christopher M Bositis; Musaku Mwenechanya; Lisa Kalungwana-Mambwe; David Bearden; Allison Navis; Melissa A Elafros; Harris Gelbard; William H Theodore; Igor J Koralnik; Jason F Okulicz; Brent A Johnson; Clara Belessiotis; Ornella Ciccone; Natalie Thornton; Melissa Tsuboyama; Omar K Siddiqi; Michael J Potchen; Izukanji Sikazwe; Gretchen L Birbeck
Journal:  Epilepsia Open       Date:  2022-04-01

4.  Disclosure to HIV-seropositive children in rural Zambia.

Authors:  Shinya Tsuzuki; Naoko Ishikawa; Hideki Miyamoto; Christopher Dube; Nangana Kayama; Janet Watala; Albert Mwango
Journal:  BMC Pediatr       Date:  2018-08-18       Impact factor: 2.125

5.  Towards elimination of mother-to-child transmission of HIV in Rwanda: a nested case-control study of risk factors for transmission.

Authors:  Eric Remera; Placidie Mugwaneza; Frédérique Chammartin; Augustin Mulindabigwi; Gentille Musengimana; Jamie I Forrest; Fabian Mwanyumba; Ng'oma Kondwani; Jeanine U Condo; David J Riedel; Edward J Mills; Sabin Nsanzimana; Heiner C Bucher
Journal:  BMC Pregnancy Childbirth       Date:  2021-04-28       Impact factor: 3.007

6.  Disclosure and health-related outcomes among children living with HIV and their caregivers.

Authors:  Margaret Amankwah-Poku; Delight Abla Klutsey; Kwaku Oppong Asante
Journal:  AIDS Res Ther       Date:  2021-04-20       Impact factor: 2.250

7.  What Factors are Responsible for Higher Prevalence of HIV Infection among Urban Women than Rural Women in Tanzania?

Authors:  Rakesh K Singh; Shraboni Patra
Journal:  Ethiop J Health Sci       Date:  2015-10

8.  HIV counselling and testing practices for children seen in an urban emergency department of a tertiary referral hospital in Dar es Salaam, Tanzania: a retrospective cross-sectional study.

Authors:  Hendry R Sawe; Juma A Mfinanga; Faith H Ringo; Victor Mwafongo; Teri A Reynolds; Michael S Runyon
Journal:  BMJ Open       Date:  2016-02-15       Impact factor: 2.692

9.  Correlates and determinants of Early Infant Diagnosis outcomes in North-Central Nigeria.

Authors:  Patrick Dakum; Monday Tola; Nta Iboro; Chukwuemeka A Okolo; Olachi Anuforom; Christopher Chime; Sam Peters; Jibreel Jumare; Obinna Ogbanufe; Aliyu Ahmad; Nicaise Ndembi
Journal:  AIDS Res Ther       Date:  2019-09-14       Impact factor: 2.250

10.  HIV testing, test results and factors influencing among infants born to HIV positive mothers in public hospitals of Mekelle City, North Ethiopia: a cross-sectional study.

Authors:  Hiluf Ebuy; Alemayehu Bekele; Getachew Redae
Journal:  BMC Infect Dis       Date:  2020-01-21       Impact factor: 3.090

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