Literature DB >> 23382277

Contemporary views on the ossification of the ligamenta flava.

Michał Kłosiński1, Janusz Skrzat, Jerzy Walocha, Ewa Mizia.   

Abstract

The ligamenta flava, together with the vertebral lamina, form the posterior wall of the spinal canal. Since they are located immediately adjacent to the nerve structures of the spinal cord, every pathology that involves hypertrophy produces neurological disturbances as a result. One of the most common reasons for hypertrophy of the ligamenta flava is heterotopic ossification. The main regions of the world where this disorder occurs are the Asian countries, especially Japan, but there are increasing numbers of such cases in other populations. The most important causes of the formation of ectopic osseous tissue in the vicinity of the ligamenta flava are thought to be mechanical stress and genetic predisposition. Treatment is mostly limited to surgical procedures. The present study is a review of the current state of our knowledge concerning the ossification of the ligamenta flava, the sequelae of this pathology, and the treatment methods.

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Year:  2012        PMID: 23382277     DOI: 10.5604/15093492.1024716

Source DB:  PubMed          Journal:  Ortop Traumatol Rehabil        ISSN: 1509-3492


  3 in total

1.  Physicochemical characterization of mineral deposits in human ligamenta flava.

Authors:  Sylwia Orzechowska; Andrzej Wróbel; Marcin Kozieł; Wiesław Łasocha; Eugeniusz Rokita
Journal:  J Bone Miner Metab       Date:  2017-04-07       Impact factor: 2.626

2.  Cyclic stretch promotes the ossification of ligamentum flavum by modulating the Indian hedgehog signaling pathway.

Authors:  Rui Gao; Changgui Shi; Chengwei Yang; Yin Zhao; Xiongsheng Chen; Xuhui Zhou
Journal:  Mol Med Rep       Date:  2020-06-02       Impact factor: 2.952

3.  Model of Pathological Collagen Mineralization Based on Spine Ligament Calcification.

Authors:  Sylwia Orzechowska; Renata Świsłocka; Włodzimierz Lewandowski
Journal:  Materials (Basel)       Date:  2020-05-04       Impact factor: 3.623

  3 in total

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