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Literature DB >> 23382001

The importance of additive and non-additive mutational effects in protein engineering.

Manfred T Reetz¹.

Abstract

Mesh：

Year: 2013 PMID： 23382001 DOI： 10.1002/anie.201207842

Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336

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32 in total

1. Non-additive stabilization by halogenated amino acids reveals protein plasticity on a sub-angstrom scale.

Authors: Azade S Hosseini; Christopher J Pace; Adam A Esposito; Jianmin Gao
Journal: Protein Sci Date: 2017-08-22 Impact factor: 6.725

2. Polyclonal Antibodies in Microplates to Predict the Maximum Adsorption Activities of Enzyme/Mutants from Cell Lysates.

Authors: Yiran Feng; Xiaolan Yang; Deqiang Wang; Xiaolei Hu; Huimin Chong; Juan Liao; Chang-Guo Zhan; Fei Liao
Journal: Protein J Date: 2017-06 Impact factor: 2.371

3. Effects of point mutations on the thermostability of B. subtilis lipase: investigating nonadditivity.

Authors: Bipin Singh; Gopalakrishnan Bulusu; Abhijit Mitra
Journal: J Comput Aided Mol Des Date: 2016-09-30 Impact factor: 3.686

4. Directed Evolution's Influence on Rapid Density Fluctuations Illustrates How Protein Dynamics Can Become Coupled to Chemistry.

Authors: Joseph W Schafer; Steven D Schwartz
Journal: ACS Catal Date: 2020-07-07 Impact factor: 13.084

The importance of additive and non-additive mutational effects in protein engineering.

1. Non-additive stabilization by halogenated amino acids reveals protein plasticity on a sub-angstrom scale.

2. Polyclonal Antibodies in Microplates to Predict the Maximum Adsorption Activities of Enzyme/Mutants from Cell Lysates.

3. Effects of point mutations on the thermostability of B. subtilis lipase: investigating nonadditivity.

4. Directed Evolution's Influence on Rapid Density Fluctuations Illustrates How Protein Dynamics Can Become Coupled to Chemistry.

Review 5. Correlated positions in protein evolution and engineering.

6. Searching for a mechanistic description of pairwise epistasis in protein systems.

Review 7. Causes of molecular convergence and parallelism in protein evolution.

8. Overriding Traditional Electronic Effects in Biocatalytic Baeyer-Villiger Reactions by Directed Evolution.

Review 9. Using experimental evolution to probe molecular mechanisms of protein function.

10. Fitness loss and library size determination in saturation mutagenesis.