Literature DB >> 23381780

Directed evolution of a synthetic RNA-protein module to create a new translational switch.

Tomoaki Hara1, Hirohide Saito, Tan Inoue.   

Abstract

A synthetic RNP-binding module was developed to produce an alternative translational switch: an in vitro selection experiment targeting a derivative of L7Ae protein (L7KK) identified a new H23 RNA aptamer that binds tightly to both L7KK and L7Ae. The switch serves as a translational OFF switch for constructing a NOR gate.

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Year:  2013        PMID： 23381780     DOI： 10.1039/c3cc38688k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  5 in total

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Authors:  Zoltán Kis; Hugo Sant'Ana Pereira; Takayuki Homma; Ryan M Pedrigi; Rob Krams
Journal:  J R Soc Interface       Date:  2015-05-06       Impact factor: 4.118

2.  A purification method for a molecular complex in which a scaffold molecule is fully loaded with heterogeneous molecules.

Authors:  Shoji J Ohuchi; Fumihiko Sagawa; Hirohisa Ohno; Tan Inoue
Journal:  PLoS One       Date:  2015-03-17       Impact factor: 3.240

Review 3.  RNA modularity for synthetic biology.

Authors:  Wade Grabow; Luc Jaeger
Journal:  F1000Prime Rep       Date:  2013-11-01

Review 4.  Molecular swarm robots: recent progress and future challenges.

Authors:  Arif Md Rashedul Kabir; Daisuke Inoue; Akira Kakugo
Journal:  Sci Technol Adv Mater       Date:  2020-06-16       Impact factor: 8.090

5.  Directed evolution of orthogonal RNA-RBP pairs through library-vs-library in vitro selection.

Authors:  Keisuke Fukunaga; Yohei Yokobayashi
Journal:  Nucleic Acids Res       Date:  2022-01-25       Impact factor: 16.971
  5 in total

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