| Literature DB >> 23381666 |
Honorine Lebraud1, Celine Cano, Benoit Carbain, Ian R Hardcastle, Ross W Harrington, Roger J Griffin, Bernard T Golding.
Abstract
Purines protected at N-9 by p-methoxybenzyl are methylated or ethylated in 2,2,2-trifluoroethanol at N-7 by trimethyl- or triethyl-oxonium borofluorate, respectively. Subjecting the resulting cationic species to microwave irradiation releases an N(7)-methyl- or ethyl-purine. This one-pot procedure is an efficient regiospecific method applicable to diverse substrates.Entities:
Mesh：
Substances：
Year: 2013 PMID： 23381666 DOI： 10.1039/c3ob27473j
Source DB: PubMed Journal: Org Biomol Chem ISSN： 1477-0520 Impact factor: 3.876