| Literature DB >> 23381314 |
Rabih Halwani1, Saleh Al-Muhsen1, Qutayba Hamid2.
Abstract
T helper 17 (Th17) cytokines are now widely believed to be critical for the regulation of various chronic immune diseases. Investigations have revealed a significant role for IL-17 cytokines in regulating inflammation and modulating lung and airway structural cells in asthma and COPD. In this review, our current understanding of the role of Th17-associated cytokines in airway diseases is summarized. Therapeutic approaches targeting IL-17 during asthma and COPD are also discussed.Entities:
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Year: 2013 PMID: 23381314 DOI: 10.1378/chest.12-0598
Source DB: PubMed Journal: Chest ISSN: 0012-3692 Impact factor: 9.410