Literature DB >> 23381108

Ubiquitin-proteasome system, a new anti-tumor target.

Wei Du1, Qi-bing Mei.   

Abstract

Entities:  

Year:  2013        PMID： 23381108      PMCID： PMC4011612          DOI： 10.1038/aps.2012.192

Source DB:  PubMed          Journal:  Acta Pharmacol Sin        ISSN： 1671-4083            Impact factor:   6.150


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  5 in total

1.  Novel DNA damage checkpoints mediating cell death induced by the NEDD8-activating enzyme inhibitor MLN4924.

Authors:  Jonathan L Blank; Xiaozhen J Liu; Katherine Cosmopoulos; David C Bouck; Khristofer Garcia; Hugues Bernard; Olga Tayber; Greg Hather; Ray Liu; Usha Narayanan; Michael A Milhollen; Eric S Lightcap
Journal:  Cancer Res       Date:  2012-10-24       Impact factor: 12.701

2.  MLN4924, a NEDD8-activating enzyme inhibitor, is active in diffuse large B-cell lymphoma models: rationale for treatment of NF-{kappa}B-dependent lymphoma.

Authors:  Michael A Milhollen; Tary Traore; Jennifer Adams-Duffy; Michael P Thomas; Allison J Berger; Lenny Dang; Lawrence R Dick; James J Garnsey; Erik Koenig; Steven P Langston; Mark Manfredi; Usha Narayanan; Mark Rolfe; Louis M Staudt; Teresa A Soucy; Jie Yu; Julie Zhang; Joseph B Bolen; Peter G Smith
Journal:  Blood       Date:  2010-06-04       Impact factor: 22.113

3.  Treatment-emergent mutations in NAEβ confer resistance to the NEDD8-activating enzyme inhibitor MLN4924.

Authors:  Michael A Milhollen; Michael P Thomas; Usha Narayanan; Tary Traore; Jessica Riceberg; Benjamin S Amidon; Neil F Bence; Joseph B Bolen; James Brownell; Lawrence R Dick; Huay-Keng Loke; Alice A McDonald; Jingya Ma; Mark G Manfredi; Todd B Sells; Mike D Sintchak; Xiaofeng Yang; Qing Xu; Erik M Koenig; James M Gavin; Peter G Smith
Journal:  Cancer Cell       Date:  2012-03-20       Impact factor: 31.743

4.  Global identification of modular cullin-RING ligase substrates.

Authors:  Michael J Emanuele; Andrew E H Elia; Qikai Xu; Claudio R Thoma; Lior Izhar; Yumei Leng; Ailan Guo; Yi-Ning Chen; John Rush; Paul Wei-Che Hsu; Hsueh-Chi Sherry Yen; Stephen J Elledge
Journal:  Cell       Date:  2011-09-29       Impact factor: 41.582

5.  An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer.

Authors:  Teresa A Soucy; Peter G Smith; Michael A Milhollen; Allison J Berger; James M Gavin; Sharmila Adhikari; James E Brownell; Kristine E Burke; David P Cardin; Stephen Critchley; Courtney A Cullis; Amanda Doucette; James J Garnsey; Jeffrey L Gaulin; Rachel E Gershman; Anna R Lublinsky; Alice McDonald; Hirotake Mizutani; Usha Narayanan; Edward J Olhava; Stephane Peluso; Mansoureh Rezaei; Michael D Sintchak; Tina Talreja; Michael P Thomas; Tary Traore; Stepan Vyskocil; Gabriel S Weatherhead; Jie Yu; Julie Zhang; Lawrence R Dick; Christopher F Claiborne; Mark Rolfe; Joseph B Bolen; Steven P Langston
Journal:  Nature       Date:  2009-04-09       Impact factor: 49.962
  5 in total
  8 in total

1.  Emerging Cancer Therapeutic Targets in Protein Homeostasis.

Authors:  Prabhakar Bastola; Derek B Oien; Megan Cooley; Jeremy Chien
Journal:  AAPS J       Date:  2018-08-27       Impact factor: 4.009

2.  L-Ornithine Schiff base-copper and -cadmium complexes as new proteasome inhibitors and apoptosis inducers in human cancer cells.

Authors:  Zhongyu Zhang; Caifeng Bi; Yuhua Fan; Nan Zhang; Rahul Deshmukh; Xingchen Yan; Xiuwen Lv; Pengfei Zhang; Xia Zhang; Q Ping Dou
Journal:  J Biol Inorg Chem       Date:  2014-12-03       Impact factor: 3.358

3.  Characterization of the anticancer effects of S115, a novel heteroaromatic thiosemicarbazone compound, in vitro and in vivo.

Authors:  Min-yu Liu; Lin Xiao; Yu-qiong Dong; Ying Liu; Li Cai; Wei-xia Xiong; Yu-long Yao; Ming Yin; Quan-hai Liu
Journal:  Acta Pharmacol Sin       Date:  2014-09-15       Impact factor: 6.150

4.  Rhodomycin A, a novel Src-targeted compound, can suppress lung cancer cell progression via modulating Src-related pathways.

Authors:  Yi-Hua Lai; Min-Hsuan Chen; Sih-Yin Lin; Sheng-Yi Lin; Yung-Hao Wong; Sung-Liang Yu; Huei-Wen Chen; Chih-Hsin Yang; Gee-Chen Chang; Jeremy J W Chen
Journal:  Oncotarget       Date:  2015-09-22

5.  AC-93253 iodide, a novel Src inhibitor, suppresses NSCLC progression by modulating multiple Src-related signaling pathways.

Authors:  Yi-Hua Lai; Sih-Yin Lin; Yu-Shan Wu; Huei-Wen Chen; Jeremy J W Chen
Journal:  J Hematol Oncol       Date:  2017-11-13       Impact factor: 17.388

Review 6.  Hybrid Chains: A Collaboration of Ubiquitin and Ubiquitin-Like Modifiers Introducing Cross-Functionality to the Ubiquitin Code.

Authors:  David A Pérez Berrocal; Katharina F Witting; Huib Ovaa; Monique P C Mulder
Journal:  Front Chem       Date:  2020-01-22       Impact factor: 5.221

Review 7.  Protein clearance strategies for disease intervention.

Authors:  Franziska Hommen; Saygın Bilican; David Vilchez
Journal:  J Neural Transm (Vienna)       Date:  2021-10-23       Impact factor: 3.575

8.  Metal-based 2,3-indolinedione derivatives as proteasome inhibitors and inducers of apoptosis in human cancer cells.

Authors:  Pengfei Zhang; Caifeng Bi; Sara M Schmitt; Xin Li; Yuhua Fan; Nan Zhang; Q Ping Dou
Journal:  Int J Mol Med       Date:  2014-07-08       Impact factor: 4.101
  8 in total

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