Literature DB >> 23380915

Antimicrobial metallopeptides with broad nuclease and ribonuclease activity.

Jeff C Joyner1, W F Hodnick, Ada S Cowan, Deepika Tamuly, Rachel Boyd, J A Cowan.   

Abstract

Metallopeptides containing both the complex Cu(2+)-glycyl-glycyl-histidine (Cu-GGH) and the sequence WRWYCR were shown to possess antimicrobial activity against a variety of pathogenic bacteria, as well as bind to and cleave a variety of nucleic acids, suggesting potential mechanisms for antimicrobial activity that involve binding and/or irreversible cleavage of bacterial nucleic acids.

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Year:  2013        PMID： 23380915      PMCID： PMC3632407          DOI： 10.1039/c3cc38977d

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  28 in total

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2.  Holliday junction-binding peptides inhibit distinct junction-processing enzymes.

Authors:  Kevin V Kepple; Jeffrey L Boldt; Anca M Segall
Journal:  Proc Natl Acad Sci U S A       Date:  2005-05-02       Impact factor: 11.205

3.  Targeted cleavage of HIV rev response element RNA by metallopeptide complexes.

Authors:  Yan Jin; J A Cowan
Journal:  J Am Chem Soc       Date:  2006-01-18       Impact factor: 15.419

4.  Mechanisms of tryptophan fluorescence shifts in proteins.

Authors:  J T Vivian; P R Callis
Journal:  Biophys J       Date:  2001-05       Impact factor: 4.033

Review 5.  Bacterial resistance to aminoglycoside antibiotics.

Authors:  J Davies; G D Wright
Journal:  Trends Microbiol       Date:  1997-06       Impact factor: 17.079

6.  Exposure of tryptophanyl residues in proteins. Quantitative determination by fluorescence quenching studies.

Authors:  M R Eftink; C A Ghiron
Journal:  Biochemistry       Date:  1976-02-10       Impact factor: 3.162

7.  DNA cleavage by copper-ATCUN complexes. Factors influencing cleavage mechanism and linearization of dsDNA.

Authors:  Yan Jin; J A Cowan
Journal:  J Am Chem Soc       Date:  2005-06-15       Impact factor: 15.419

8.  Structure of the A site of Escherichia coli 16S ribosomal RNA complexed with an aminoglycoside antibiotic.

Authors:  D Fourmy; M I Recht; S C Blanchard; J D Puglisi
Journal:  Science       Date:  1996-11-22       Impact factor: 47.728

9.  Drug-resistant Salmonella from animals fed antimicrobials.

Authors:  S D Holmberg; M T Osterholm; K A Senger; M L Cohen
Journal:  N Engl J Med       Date:  1984-09-06       Impact factor: 91.245

Review 10.  Metal complex catalysis in living biological systems.

Authors:  Pijus K Sasmal; Craig N Streu; Eric Meggers
Journal:  Chem Commun (Camb)       Date:  2013-02-25       Impact factor: 6.222
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  11 in total

1.  Analysis of Structure-Activity Relationships Based on the Hepatitis C Virus SLIIb Internal Ribosomal Entry Sequence RNA-Targeting GGHYRFK⋅Cu Complex.

Authors:  Martin James Ross; Insiya Fidai; James A Cowan
Journal:  Chembiochem       Date:  2017-08-07       Impact factor: 3.164

2.  DNA Cleaving "Tandem-Array" Metallopeptides Activated With KHSO5: Towards the Development of Multi-Metallated Bioactive Conjugates and Compounds.

Authors:  Mark A Lewis; Katie M Williams; Ya-Yin Fang; Franklin A Schultz; Eric C Long
Journal:  Curr Bioact Compd       Date:  2014

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4.  Improved bioactivity of antimicrobial peptides by addition of amino-terminal copper and nickel (ATCUN) binding motifs.

Authors:  M Daben Libardo; Jorge L Cervantes; Juan C Salazar; Alfredo M Angeles-Boza
Journal:  ChemMedChem       Date:  2014-05-06       Impact factor: 3.466

5.  Nuclease activity gives an edge to host-defense peptide piscidin 3 over piscidin 1, rendering it more effective against persisters and biofilms.

Authors:  M Daben J Libardo; Ali A Bahar; Buyong Ma; Riqiang Fu; Laura E McCormick; Jun Zhao; Scott A McCallum; Ruth Nussinov; Dacheng Ren; Alfredo M Angeles-Boza; Myriam L Cotten
Journal:  FEBS J       Date:  2017-09-30       Impact factor: 5.542

Review 6.  Metal complexes promoting catalytic cleavage of nucleic acids-biochemical tools and therapeutics.

Authors:  Zhen Yu; J A Cowan
Journal:  Curr Opin Chem Biol       Date:  2017-11-15       Impact factor: 8.822

Review 7.  Target-directed catalytic metallodrugs.

Authors:  J C Joyner; J A Cowan
Journal:  Braz J Med Biol Res       Date:  2013-07-02       Impact factor: 2.590

Review 8.  Amphiphilic Aminoglycosides as Medicinal Agents.

Authors:  Clément Dezanet; Julie Kempf; Marie-Paule Mingeot-Leclercq; Jean-Luc Décout
Journal:  Int J Mol Sci       Date:  2020-10-08       Impact factor: 5.923

Review 9.  Metallo-polyelectrolytes as a class of ionic macromolecules for functional materials.

Authors:  Tianyu Zhu; Ye Sha; Jing Yan; Parasmani Pageni; Md Anisur Rahman; Yi Yan; Chuanbing Tang
Journal:  Nat Commun       Date:  2018-10-18       Impact factor: 14.919

10.  How Oxygen Availability Affects the Antimicrobial Efficacy of Host Defense Peptides: Lessons Learned from Studying the Copper-Binding Peptides Piscidins 1 and 3.

Authors:  Adenrele Oludiran; David S Courson; Malia D Stuart; Anwar R Radwan; John C Poutsma; Myriam L Cotten; Erin B Purcell
Journal:  Int J Mol Sci       Date:  2019-10-24       Impact factor: 5.923
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