Literature DB >> 23379421

Sertoli-Leydig cell tumors: current status of surgical management: literature review and proposal of treatment.

Pietro Litta1, Carlo Saccardi, Lorena Conte, Anna Codroma, Stefano Angioni, Roberto Mioni.   

Abstract

To identify the appropriate management we review the current literature on the diagnostic and different surgical procedures to which the patients affected by Sertoli-Leyding cell tumors (SLCTs) were submitted. Through the description of a case report we also propose an interdisciplinary diagnostic approach and a laparoscopic surgical staging, with a long-term follow-up. The analysis shows that pelvic ultrasound is primary diagnostic procedure, and only 36% of publications clearly describe to have performed more specific investigation. The hormone assessment is performed in the presence of specific endocrine symptoms. Laparoscopic approach is chosen by a few surgeon. Laparotomic surgery is preferred based in not recent recommendations for ovarian cancer treatment, although it is demonstrated the efficacy and safety of laparoscopy in the treatment of ovarian epithelial tumors. Different steps that are usually used for oncological ovarian cancer staging are not always performed. Conservative and fertility sparing surgery is commonly accepted, and even preferred due to the young age of patients. In the surgical treatment of SLCTs is necessary to adopt common guidelines, and evenly define the steps that the patient should be submitted. If are observed epithelial cancer oncological principles, laparoscopic surgery should be the approach of choice for these patients.

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Year:  2013        PMID: 23379421     DOI: 10.3109/09513590.2012.754878

Source DB:  PubMed          Journal:  Gynecol Endocrinol        ISSN: 0951-3590            Impact factor:   2.260


  7 in total

1.  Leydig cell tumor incidentally detected by fused FDG-PET/MRI.

Authors:  Giorgio Treglia; Vittoria Espeli; Luca Giovanella
Journal:  Endocrine       Date:  2015-01-31       Impact factor: 3.633

2.  Fertility-sparing management and obstetric outcomes in a 20-year-old patient with a Sertoli-Leydig cell tumor of the ovary: A case report and review of the literature.

Authors:  Thomas Stavrakis; Ioannis Kalogiannidis; Stamatios Petousis; Chrisoula Tsompanidou; Dimitris Delkos; Nikolaos Prapas; David Rousso
Journal:  Oncol Lett       Date:  2016-06-09       Impact factor: 2.967

Review 3.  [Grading of gynecological tumors : Current aspects].

Authors:  L-C Horn; D Mayr; C E Brambs; J Einenkel; I Sändig; K Schierle
Journal:  Pathologe       Date:  2016-07       Impact factor: 1.011

4.  A Case Report: Ovarian Sertoli-Leydig Cell Tumor With Hyperestrogenism and Endometrial Hyperplasia in a Postmenopausal Woman.

Authors:  Yoko Tsuzuki; Iwaho Kikuchi; Michio Nojima; Koyo Yoshida; Akane Hashizume; Shigeki Tomita
Journal:  Jpn Clin Med       Date:  2017-03-14

5.  [Sertoli-Leydig cell tumor of the ovary: case study of a 22-year old woman].

Authors:  Diallo Moussa; Diouf Abdoul Aziz; Diallo Astou Coly Niassy; Koulimaya Cyre Espérence; Niang Youssou; Moreau Jean Charles; Diouf Alassane
Journal:  Pan Afr Med J       Date:  2016-09-28

6.  Sertoli-Leydig Cell Ovarian Tumors: Is Fertility or Endocrine-Sparing Surgery an Option upon Relapse?

Authors:  Stéphanie J Seidler; Alexandre Huber; James Nef; Daniela E Huber
Journal:  Case Rep Oncol       Date:  2020-07-31

7.  Sertoli-Leydig cell tumors of ovary: A case series.

Authors:  Qiong Xu; Yu Zou; Xiao Fei Zhang
Journal:  Medicine (Baltimore)       Date:  2018-10       Impact factor: 1.817

  7 in total

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