UNLABELLED: With conventional imaging techniques such as planar lymphoscintigraphy and SPECT/CT, preoperative sentinel node (SN) identification can be difficult when the SN is near the primary tumor, as is the case in floor-of-mouth carcinomas. PET/CT lymphoscintigraphy may improve the detection and localization of such SNs. METHODS: In this study, the clinical feasibility of PET/CT lymphoscintigraphy using (89)Zr-nanocolloidal albumin was evaluated in 5 oral cancer patients. PET/CT lymphoscintigraphy was performed after peritumoral injection of (89)Zr-nanocolloidal albumin. The routine SN procedure, including SPECT/CT using (99m)Tc-nanocolloidal albumin, was performed on the same patients 7-9 d after the injection of (89)Zr-nanocolloidal albumin. RESULTS: Comparison of radiocolloid distribution on PET/CT and SPECT/CT showed identical drainage patterns. Moreover, PET/CT was able to identify additional foci near the primary tumor. CONCLUSION: This pilot PET/CT study on SN detection indicated that lymphoscintigraphy using (89)Zr-nanocolloidal albumin is feasible.
UNLABELLED: With conventional imaging techniques such as planar lymphoscintigraphy and SPECT/CT, preoperative sentinel node (SN) identification can be difficult when the SN is near the primary tumor, as is the case in floor-of-mouth carcinomas. PET/CT lymphoscintigraphy may improve the detection and localization of such SNs. METHODS: In this study, the clinical feasibility of PET/CT lymphoscintigraphy using (89)Zr-nanocolloidal albumin was evaluated in 5 oral cancerpatients. PET/CT lymphoscintigraphy was performed after peritumoral injection of (89)Zr-nanocolloidal albumin. The routine SN procedure, including SPECT/CT using (99m)Tc-nanocolloidal albumin, was performed on the same patients 7-9 d after the injection of (89)Zr-nanocolloidal albumin. RESULTS: Comparison of radiocolloid distribution on PET/CT and SPECT/CT showed identical drainage patterns. Moreover, PET/CT was able to identify additional foci near the primary tumor. CONCLUSION: This pilot PET/CT study on SN detection indicated that lymphoscintigraphy using (89)Zr-nanocolloidal albumin is feasible.
Authors: Christina Bluemel; Domenico Rubello; Patrick M Colletti; Remco de Bree; Ken Herrmann Journal: Eur J Nucl Med Mol Imaging Date: 2015-04-28 Impact factor: 9.236
Authors: Daniel L J Thorek; David Ulmert; Ndeye-Fatou M Diop; Mihaela E Lupu; Michael G Doran; Ruimin Huang; Diane S Abou; Steven M Larson; Jan Grimm Journal: Nat Commun Date: 2014 Impact factor: 14.919
Authors: Rutger Mahieu; Gerard C Krijger; F F Tessa Ververs; Remmert de Roos; Remco de Bree; Bart de Keizer Journal: Eur J Nucl Med Mol Imaging Date: 2021-04 Impact factor: 9.236
Authors: Nynke S van den Berg; Hervé Simon; Gijs H Kleinjan; Thijs Engelen; Anton Bunschoten; Mick M Welling; Bernard M Tijink; Simon Horenblas; Jacques Chambron; Fijs W B van Leeuwen Journal: Eur J Nucl Med Mol Imaging Date: 2015-06-25 Impact factor: 9.236
Authors: Rutger Mahieu; Dominique N V Donders; Gerard C Krijger; F F Tessa Ververs; Remmert de Roos; John L M M Bemelmans; Rob van Rooij; Remco de Bree; Bart de Keizer Journal: Eur J Nucl Med Mol Imaging Date: 2021-12-28 Impact factor: 10.057
Authors: Putthiporn Charoenphun; Levente K Meszaros; Krisanat Chuamsaamarkkee; Ehsan Sharif-Paghaleh; James R Ballinger; Trevor J Ferris; Michael J Went; Gregory E D Mullen; Philip J Blower Journal: Eur J Nucl Med Mol Imaging Date: 2014-10-31 Impact factor: 9.236
Authors: Inne J den Toom; Annelies van Schie; Stijn van Weert; K Hakki Karagozoglu; Elisabeth Bloemena; Otto S Hoekstra; Remco de Bree Journal: Eur J Nucl Med Mol Imaging Date: 2017-01-29 Impact factor: 9.236