Literature DB >> 23378470

Geriatric Nutritional Risk Index as a prognostic factor in peritoneal dialysis patients.

Seok Hui Kang1, Kyu Hyang Cho, Jong Won Park, Kyung Woo Yoon, Jun Young Do.   

Abstract

BACKGROUND: The Geriatric Nutritional Risk Index (GNRI) might be a useful screening tool for malnutrition in dialysis patients. However, data concerning the GNRI as a prognostic factor in peritoneal dialysis (PD) patients are scarce.
METHODS: We reviewed the medical records at Yeungnam University Hospital in Korea to identify all adults (>18 years) who received PD; 486 patients were enrolled in the study.
RESULTS: The initial low, middle, and high GNRI tertiles included 162, 166, and 158 patients respectively. Significant correlations were noted between the initial GNRI and body mass index, creatinine, albumin, arm circumference, fat mass index, and comorbidities. The cut-off value for the time-averaged GNRI over 1 year was 96.4, and the sensitivity and specificity for a diagnosis of a decline in lean mass were 77.1% and 40.0% respectively. A multivariate analysis adjusted for age, risk according to the Davies comorbidity index, and C-reactive protein showed that an low initial GNRI tertile was associated with mortality in PD patients.
CONCLUSIONS: The GNRI is a simple method for predicting nutrition status and clinical outcome in PD patients.

Entities:  

Keywords:  Geriatric Nutritional Risk Index; lean mass; nutrition; prognostic factor

Mesh:

Year:  2013        PMID: 23378470      PMCID: PMC3707719          DOI: 10.3747/pdi.2012.00018

Source DB:  PubMed          Journal:  Perit Dial Int        ISSN: 0896-8608            Impact factor:   1.756


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