Literature DB >> 23378233

Mortality from meningococcal disease by day of the week: English national linked database study.

Michael J Goldacre1, Jenny J Maisonneuve.   

Abstract

BACKGROUND: There are concerns that quality of medical care may be poorer on weekends than weekdays. Invasive meningococcal disease, comprising septicaemia and meningitis, is often life threatening unless it is immediately and effectively treated regardless of day of the week. We test the hypothesis that numbers of deaths from meningococcal disease outside hospital without admission, and case fatality rates (CFRs) following admission, did not differ between weekends and weekdays.
METHODS: Analysis of linked hospital and mortality data, England, 1999-2010.
RESULTS: The study comprised 19 729 people. There was no significant difference between days of the week in the number of deaths outside hospital in people who never reached hospital care. Of people who were admitted, CFRs for weekend and weekday admissions were the same: 4.9% (262/5315) on weekends and 4.9% (678/13 798) on weekdays. We undertook sensitivity analyses and analysed multivariate models but, however the data were analysed, the result of no 'weekend effect' remained.
CONCLUSIONS: There are few, if any, other acute diseases in which the difference in mortality outcome between no treatment and effective treatment is so great and unequivocally related to care itself. There was no evidence of excess deaths from meningococcal disease associated with weekend care.

Entities:  

Keywords:  communicable diseases; emergency care; health services

Mesh:

Year:  2013        PMID: 23378233     DOI: 10.1093/pubmed/fdt004

Source DB:  PubMed          Journal:  J Public Health (Oxf)        ISSN: 1741-3842            Impact factor:   2.341


  4 in total

1.  Awareness of meningococcal disease among travelers from the United Kingdom to the meningitis belt in Africa.

Authors:  Anna L Goodman; Cristina Masuet-Aumatell; Jay Halbert; Jane N Zuckerman
Journal:  Am J Trop Med Hyg       Date:  2014-06-02       Impact factor: 2.345

Review 2.  Invasive meningococcal disease in older adults in North America and Europe: is this the time for action? A review of the literature.

Authors:  Sandra Guedes; Isabelle Bertrand-Gerentes; Keith Evans; Florence Coste; Philipp Oster
Journal:  BMC Public Health       Date:  2022-02-23       Impact factor: 3.295

3.  Outcomes of acute upper gastrointestinal bleeding in relation to timing of endoscopy and the experience of endoscopist: a tertiary center experience.

Authors:  Noor Mohammed; Amer Rehman; Mark Thomas Swinscoe; Pradeep Mundre; Bjorn Rembacken
Journal:  Endosc Int Open       Date:  2016-03-03

4.  The weekend effect: does hospital mortality differ by day of the week? A systematic review and meta-analysis.

Authors:  Kate Honeyford; Elizabeth Cecil; Michelle Lo; Alex Bottle; Paul Aylin
Journal:  BMC Health Serv Res       Date:  2018-11-20       Impact factor: 2.655

  4 in total

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