BACKGROUND: Gallstones (GS) in the gallbladder (GB) can be responsible for a whole spectrum of disease entities which may lead to a surgical emergency with high mortality. Diabetes mellitus (DM) is a debilitating disease that affects all systems in the body, and literature documents a higher incidence of gallstone disease (GSD) and its complications in diabetics than in the non-diabetic population. Most local studies on the association between GS formation and DM have focused on type 2 diabetics. This study was therefore designed to determine the prevalence of GS in both type 1 and type 2 DM and elucidate the demographic and social factors associated with formation of GS in diabetic patients. MATERIALS AND METHODS: Four hundred diabetic patients aged between 15 and 82 years had abdominal ultrasound to diagnose or exclude the presence of GS. RESULTS: GS was found in 70 (17.5%) of the 400 patients. Positive cases had a male to female ratio of 3:4 and 59 (51.92%) were above the age of 40 years with type 2 DM. Body mass index (BMI) greater than 25 kg/m 2 was seen in 56 (48.3%) patients; smoking and alcohol intake were insignificantly implicated. Jaundice was recorded in 8 (11.4%) while abdominal pain was in 24 (34.3%) patients, and 52 (74.3%) patients of those with GSD had had diabetes for more than 4 years. CONCLUSION: GSD in DM is influenced significantly by age, BMI, and duration of the disease, while gender, social factors, and parity do not influence as strong associated factors.
BACKGROUND: Gallstones (GS) in the gallbladder (GB) can be responsible for a whole spectrum of disease entities which may lead to a surgical emergency with high mortality. Diabetes mellitus (DM) is a debilitating disease that affects all systems in the body, and literature documents a higher incidence of gallstone disease (GSD) and its complications in diabetics than in the non-diabetic population. Most local studies on the association between GS formation and DM have focused on type 2 diabetics. This study was therefore designed to determine the prevalence of GS in both type 1 and type 2 DM and elucidate the demographic and social factors associated with formation of GS in diabeticpatients. MATERIALS AND METHODS: Four hundred diabeticpatients aged between 15 and 82 years had abdominal ultrasound to diagnose or exclude the presence of GS. RESULTS:GS was found in 70 (17.5%) of the 400 patients. Positive cases had a male to female ratio of 3:4 and 59 (51.92%) were above the age of 40 years with type 2 DM. Body mass index (BMI) greater than 25 kg/m 2 was seen in 56 (48.3%) patients; smoking and alcohol intake were insignificantly implicated. Jaundice was recorded in 8 (11.4%) while abdominal pain was in 24 (34.3%) patients, and 52 (74.3%) patients of those with GSD had had diabetes for more than 4 years. CONCLUSION:GSD in DM is influenced significantly by age, BMI, and duration of the disease, while gender, social factors, and parity do not influence as strong associated factors.
Authors: Michael A Nauck; Marie Louise Muus Ghorbani; Eskil Kreiner; Hans A Saevereid; John B Buse Journal: Diabetes Care Date: 2019-08-09 Impact factor: 19.112
Authors: Ahmed Omer Almobarak; Ayat Jervase; Aza Abdelrahman Fadl; Nur Ibrahim Ali Garelnabi; Suzan Al Hakem; Tarig Mohamed Hussein; Amro Ahmad Aljack Ahmad; Inas Salah El-den Ahmed; Safaa Badi; Mohamed H Ahmed Journal: Transl Gastroenterol Hepatol Date: 2020-04-05
Authors: Jean Jacques Noubiap; Jobert Richie Nansseu; Francky Teddy Endomba; Anderson Ngouo; Jan René Nkeck; Ulrich Flore Nyaga; Arnaud D Kaze; Jean Joel Bigna Journal: Sci Rep Date: 2019-01-24 Impact factor: 4.379