Literature DB >> 23377207

When the drugs don't work: the potential of glutamatergic antipsychotics in schizophrenia.

Evangelos Papanastasiou1, James M Stone, Sukhi Shergill.   

Abstract

Currently available antipsychotic drugs target dopaminergic neurotransmission. Many patients do not respond fully to these treatments, and there has been considerable effort to investigate alternative targets. Here we summarise the rationale and recent evidence supporting efforts to develop glutamatergic antipsychotic drugs.

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Year:  2013        PMID: 23377207     DOI: 10.1192/bjp.bp.112.110999

Source DB:  PubMed          Journal:  Br J Psychiatry        ISSN: 0007-1250            Impact factor:   9.319


  8 in total

Review 1.  Antipsychotic treatment modulates glutamate transport and NMDA receptor expression.

Authors:  Mathias Zink; Susanne Englisch; Andrea Schmitt
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2014-09-12       Impact factor: 5.270

2.  Dysfunctional Striatal Systems in Treatment-Resistant Schizophrenia.

Authors:  Thomas P White; Rebekah Wigton; Dan W Joyce; Tracy Collier; Alex Fornito; Sukhwinder S Shergill
Journal:  Neuropsychopharmacology       Date:  2015-09-09       Impact factor: 7.853

Review 3.  Ketamine as the prototype glutamatergic antidepressant: pharmacodynamic actions, and a systematic review and meta-analysis of efficacy.

Authors:  Caroline Caddy; Giovanni Giaroli; Thomas P White; Sukhwinder S Shergill; Derek K Tracy
Journal:  Ther Adv Psychopharmacol       Date:  2014-04

4.  Prevalence of serum N-methyl-D-aspartate receptor autoantibodies in refractory psychosis.

Authors:  Katherine Beck; John Lally; Sukhwinder S Shergill; Michael A P Bloomfield; James H MacCabe; Fiona Gaughran; Oliver D Howes
Journal:  Br J Psychiatry       Date:  2014-11-27       Impact factor: 9.319

5.  Unheard voices: outcomes of tertiary care for treatment-refractory psychosis.

Authors:  S Neil Sarkar; Derek K Tracy; Maria-Jesus Mateos Fernandez; Natasza Nalesnik; Gurbinder Dhillon; Juliana Onwumere; Anne-Marye Prins; Karen Schepman; Tracy Collier; Thomas P White; Anita Patel; Fiona Gaughran; Sukhwinder S Shergill
Journal:  Psychiatr Bull (2014)       Date:  2014-04

Review 6.  An Overview of the Association between Schizotypy and Dopamine.

Authors:  Christine Mohr; Ulrich Ettinger
Journal:  Front Psychiatry       Date:  2014-12-19       Impact factor: 4.157

7.  Service users' and carers' views on research towards stratified medicine in psychiatry: a qualitative study.

Authors:  Diana Rose; Constantina Papoulias; James MacCabe; Jennifer Walke
Journal:  BMC Res Notes       Date:  2015-09-28

Review 8.  Antipsychotic Drugs: From Receptor-binding Profiles to Metabolic Side Effects.

Authors:  Spyridon Siafis; Dimitrios Tzachanis; Myrto Samara; Georgios Papazisis
Journal:  Curr Neuropharmacol       Date:  2018       Impact factor: 7.363

  8 in total

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