Literature DB >> 23377028

miR-29b moulds the tumour microenvironment to repress metastasis.

Sonia A Melo1, Raghu Kalluri.   

Abstract

Tumour cells are influenced by their microenvironment, which can promote uncontrolled growth, invasion and metastasis. The GATA3 transcription factor is now shown to regulate the tumour microenvironment by inducing the expression of miR-29b in cancer cells. This microRNA in turn inhibits the expression of genes involved in angiogenesis and extracellular matrix signalling and remodelling to suppress metastasis.

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Year:  2013        PMID： 23377028     DOI： 10.1038/ncb2684

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN： 1465-7392            Impact factor:   28.824


  18 in total

Review 1.  The functions of animal microRNAs.

Authors:  Victor Ambros
Journal:  Nature       Date:  2004-09-16       Impact factor: 49.962

Review 2.  Circulating microRNAs: a novel class of biomarkers to diagnose and monitor human cancers.

Authors:  Ke Zen; Chen-Yu Zhang
Journal:  Med Res Rev       Date:  2010-11-09       Impact factor: 12.944

Review 3.  Mechanisms of metastasis: epithelial-to-mesenchymal transition and contribution of tumor microenvironment.

Authors:  Joyce C Tse; Raghu Kalluri
Journal:  J Cell Biochem       Date:  2007-07-01       Impact factor: 4.429

Review 4.  Fibroblasts in cancer.

Authors:  Raghu Kalluri; Michael Zeisberg
Journal:  Nat Rev Cancer       Date:  2006-05       Impact factor: 60.716

5.  miR-29b regulates migration of human breast cancer cells.

Authors:  Chen Wang; Zhen Bian; Da Wei; Jian-guo Zhang
Journal:  Mol Cell Biochem       Date:  2011-02-26       Impact factor: 3.396

6.  GATA3 inhibits breast cancer metastasis through the reversal of epithelial-mesenchymal transition.

Authors:  Wei Yan; Qing Jackie Cao; Richard B Arenas; Brooke Bentley; Rong Shao
Journal:  J Biol Chem       Date:  2010-02-26       Impact factor: 5.157

7.  MBP-1 upregulates miR-29b that represses Mcl-1, collagens, and matrix-metalloproteinase-2 in prostate cancer cells.

Authors:  Robert Steele; Justin L Mott; Ratna B Ray
Journal:  Genes Cancer       Date:  2010-04-01

8.  GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression.

Authors:  Jonathan Chou; Jeffrey H Lin; Audrey Brenot; Jung-whan Kim; Sylvain Provot; Zena Werb
Journal:  Nat Cell Biol       Date:  2013-01-27       Impact factor: 28.824

9.  The Role of miRNAs as Key Regulators in the Neoplastic Microenvironment.

Authors:  K K Wentz-Hunter; J A Potashkin
Journal:  Mol Biol Int       Date:  2011-04-06

10.  Association of GATA3, P53, Ki67 status and vascular peritumoral invasion are strongly prognostic in luminal breast cancer.

Authors:  Jocelyne Jacquemier; Emmanuelle Charafe-Jauffret; Florence Monville; Benjamin Esterni; Jean Marc Extra; Gilles Houvenaeghel; Luc Xerri; François Bertucci; Daniel Birnbaum
Journal:  Breast Cancer Res       Date:  2009-04-30       Impact factor: 6.466
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  23 in total

1.  General rules for functional microRNA targeting.

Authors:  Doyeon Kim; You Me Sung; Jinman Park; Sukjun Kim; Jongkyu Kim; Junhee Park; Haeok Ha; Jung Yoon Bae; SoHui Kim; Daehyun Baek
Journal:  Nat Genet       Date:  2016-10-24       Impact factor: 38.330

2.  Mesenchymal stem cells correct impaired diabetic wound healing by decreasing ECM proteolysis.

Authors:  Junwang Xu; Carlos Zgheib; Maggie M Hodges; Robert C Caskey; Junyi Hu; Kenneth W Liechty
Journal:  Physiol Genomics       Date:  2017-08-25       Impact factor: 3.107

Review 3.  Posttranscriptional regulation of intestinal epithelial integrity by noncoding RNAs.

Authors:  Jun-Yao Wang; Lan Xiao; Jian-Ying Wang
Journal:  Wiley Interdiscip Rev RNA       Date:  2016-10-04       Impact factor: 9.957

4.  Downregulation of miR-193a-5p correlates with lymph node metastasis and poor prognosis in colorectal cancer.

Authors:  Peng Zhang; Deng-Bo Ji; Hai-Bo Han; Yun-Fei Shi; Chang-Zheng Du; Jin Gu
Journal:  World J Gastroenterol       Date:  2014-09-14       Impact factor: 5.742

5.  Modulation by miR-29b of intestinal epithelium homoeostasis through the repression of menin translation.

Authors:  Miao Ouyang; Weijie Su; Lan Xiao; Jaladanki N Rao; Liping Jiang; Yanwu Li; Douglas J Turner; Myriam Gorospe; Jian-Ying Wang
Journal:  Biochem J       Date:  2015-01-15       Impact factor: 3.857

Review 6.  Cell density regulates cancer metastasis via the Hippo pathway.

Authors:  Ghada M Sharif; Anton Wellstein
Journal:  Future Oncol       Date:  2015-11-12       Impact factor: 3.404

7.  Regulation of Intestinal Epithelial Barrier Function by Long Noncoding RNA uc.173 through Interaction with MicroRNA 29b.

Authors:  Jun-Yao Wang; Yu-Hong Cui; Lan Xiao; Hee Kyoung Chung; Yunzhan Zhang; Jaladanki N Rao; Myriam Gorospe; Jian-Ying Wang
Journal:  Mol Cell Biol       Date:  2018-06-14       Impact factor: 4.272

Review 8.  Illustrating the interplay between the extracellular matrix and microRNAs.

Authors:  Anna M Piccinini; Kim S Midwood
Journal:  Int J Exp Pathol       Date:  2014-04-25       Impact factor: 1.925

9.  MicroRNA-16 suppresses metastasis in an orthotopic, but not autochthonous, mouse model of soft tissue sarcoma.

Authors:  Mohit Sachdeva; Melody J Whitley; Jeffrey K Mito; Yan Ma; Dina C Lev; Diana M Cardona; David G Kirsch
Journal:  Dis Model Mech       Date:  2015-06-04       Impact factor: 5.758

10.  Cell growth density modulates cancer cell vascular invasion via Hippo pathway activity and CXCR2 signaling.

Authors:  G M Sharif; M O Schmidt; C Yi; Z Hu; B R Haddad; E Glasgow; A T Riegel; A Wellstein
Journal:  Oncogene       Date:  2015-03-16       Impact factor: 9.867
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