| Literature DB >> 23375792 |
Jay Parrish1, Leah Tong, Michael Wang, Xiaowu Chen, Eric B Lansdon, Carina Cannizzaro, Xubin Zheng, Manoj C Desai, Lianhong Xu.
Abstract
A series of nevirapine-based analogues containing the phosphonate functionality were prepared and evaluated in vitro against HIV RT. The effect of the phosphonate was evaluated against the wild type and Y181C HIV replication. An in vivo PK study was performed on a select analogue.Entities:
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Year: 2012 PMID： 23375792 DOI： 10.1016/j.bmcl.2012.12.049
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823