| Literature DB >> 23375791 |
Ian E Crandall1, Bohang Zhao, Jason Z Vlahakis, Walter A Szarek.
Abstract
The interaction between DNA and members of series of bivalent imidazole compounds, monovalent and bivalent imidazolium compounds, and monovalent and bivalent tetrazolium compounds, which had been synthesized and evaluated for their anti-Plasmodium activity, has been examined using the displacement of SYBR Green I as a measure of competitive binding. The degree of interaction with DNA appears to be dependent on both hydrophobic and charge-pairing interactions.Entities:
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Year: 2012 PMID： 23375791 DOI： 10.1016/j.bmcl.2012.11.106
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823