BACKGROUND: Transjugular intrahepatic portosystemic stent shunt (TIPS) has become the modality of choice for complicated portal decompression. This study was undertaken to determine outcomes after TIPS and the usefulness of TIPS as a "bridge" to transplantation. METHODS: Patients undergoing TIPS from 2001 to 2010 at a teaching hospital with a transplant program were studied. The median data are presented. RESULTS: TIPS was undertaken in 256 patients. TIPS decreased portal vein-inferior vena cava (IVC) gradients from 17 to 5 mm Hg (P < .001). Reinterventions were undertaken in 54 patients (21%). Survival after TIPS was 26 months; liver transplantation was undertaken in 35 (14%) patients. CONCLUSIONS: TIPS effectively decompresses portal hypertension but leads to frequent reinterventions and short survival. After TIPS, liver transplantation is uncommonly undertaken. TIPS is a "bridge" to transplantation that is seldom "crossed," and TIPS continues to be plagued by frequent reinterventions. Outcomes after TIPS and the infrequency of transplantation after TIPS make it difficult to recommend on merit.
BACKGROUND: Transjugular intrahepatic portosystemic stent shunt (TIPS) has become the modality of choice for complicated portal decompression. This study was undertaken to determine outcomes after TIPS and the usefulness of TIPS as a "bridge" to transplantation. METHODS:Patients undergoing TIPS from 2001 to 2010 at a teaching hospital with a transplant program were studied. The median data are presented. RESULTS: TIPS was undertaken in 256 patients. TIPS decreased portal vein-inferior vena cava (IVC) gradients from 17 to 5 mm Hg (P < .001). Reinterventions were undertaken in 54 patients (21%). Survival after TIPS was 26 months; liver transplantation was undertaken in 35 (14%) patients. CONCLUSIONS: TIPS effectively decompresses portal hypertension but leads to frequent reinterventions and short survival. After TIPS, liver transplantation is uncommonly undertaken. TIPS is a "bridge" to transplantation that is seldom "crossed," and TIPS continues to be plagued by frequent reinterventions. Outcomes after TIPS and the infrequency of transplantation after TIPS make it difficult to recommend on merit.
Authors: Andrew J Woerner; David S Shin; Jeffrey Forris Beecham Chick; Kevin S H Koo; Evelyn K Hsu; Elizabeth R Tang; Eric J Monroe Journal: Pediatr Radiol Date: 2021-03-30
Authors: Hyung Ki Kim; Yoon Jun Kim; Woo Jin Chung; Soon Sun Kim; Jae Jun Shim; Moon Seok Choi; Do Young Kim; Dae Won Jun; Soon Ho Um; Sung Jae Park; Hyun Young Woo; Young Kul Jung; Soon Koo Baik; Moon Young Kim; Soo Young Park; Jae Myeong Lee; Young Seok Kim Journal: Clin Mol Hepatol Date: 2014-03-26
Authors: Min Lang; Angela L Lang; Brian Q Tsui; Weiping Wang; Brian K Erly; Bo Shen; Baljendra Kapoor Journal: Gastroenterol Rep (Oxf) Date: 2020-12-03