Oliver Geier1, Andreas Max Weng2, Andreas Toepell3, Dietbert Hahn3, Matthias Spindler4, Meinrad Beer5, Herbert Köstler6. 1. The Intervention Centre, Oslo University Hospital, Oslo, Norway; Institute of Radiology, University of Würzburg, Würzburg, Germany. 2. Institute of Radiology, University of Würzburg, Würzburg, Germany. Electronic address: weng@roentgen.uni-wuerzburg.de. 3. Institute of Radiology, University of Würzburg, Würzburg, Germany. 4. Department of Internal Medicine, University of Würzburg, Würzburg, Germany. 5. Institute of Radiology, University of Würzburg, Würzburg, Germany; Department of Pediatric Radiology, Medical University Graz, Graz, Austria. 6. Institute of Radiology, University of Würzburg, Würzburg, Germany; Comprehensive Heart Failure Center, University of Würzburg, Würzburg, Germany.
Abstract
PURPOSE: Phosphorous metabolite ratios in human myocardium were determined by a combination of acquisition weighted CSI and a SLOOP evaluation and the results were compared to corresponding SLOOP experiments using standard CSI. MATERIALS AND METHODS: 10 healthy subjects were examined at 1.5 T using both standard CSI and acquisition weighted CSI. Both experiments were performed with a similar acquisition time and the same spatial resolution. The PCr/ATP ratio was determined and the localization properties of both experiments were compared. RESULTS: The PCr/ATP ratio of 2.2±0.4 found for the experiment using acquisition weighted CSI was almost identical to the value of 2.0±0.4 for standard CSI. The sensitivity and the localization properties improved in all subjects using SLOOP evaluation of the acquisition weighted sampling in comparison to the standard CSI acquisition with an average of 3% and 18%, respectively. CONCLUSION: The employment of acquisition weighting allows for a further improvement of the (31)P SLOOP spectroscopy of the human heart.
PURPOSE:Phosphorous metabolite ratios in human myocardium were determined by a combination of acquisition weighted CSI and a SLOOP evaluation and the results were compared to corresponding SLOOP experiments using standard CSI. MATERIALS AND METHODS: 10 healthy subjects were examined at 1.5 T using both standard CSI and acquisition weighted CSI. Both experiments were performed with a similar acquisition time and the same spatial resolution. The PCr/ATP ratio was determined and the localization properties of both experiments were compared. RESULTS: The PCr/ATP ratio of 2.2±0.4 found for the experiment using acquisition weighted CSI was almost identical to the value of 2.0±0.4 for standard CSI. The sensitivity and the localization properties improved in all subjects using SLOOP evaluation of the acquisition weighted sampling in comparison to the standard CSI acquisition with an average of 3% and 18%, respectively. CONCLUSION: The employment of acquisition weighting allows for a further improvement of the (31)P SLOOP spectroscopy of the human heart.
Authors: Martin Christa; Andreas M Weng; Bettina Geier; Caroline Wörmann; Anne Scheffler; Leane Lehmann; Johannes Oberberger; Bettina J Kraus; Stefanie Hahner; Stefan Störk; Thorsten Klink; Wolfgang R Bauer; Fabian Hammer; Herbert Köstler Journal: Eur Heart J Cardiovasc Imaging Date: 2019-03-01 Impact factor: 6.875