Literature DB >> 23374336

The role of telomeres in stem cells and cancer.

Cagatay Günes1, K Lenhard Rudolph.   

Abstract

Telomere shortening impairs proliferation of transformed cells but also leads to cancer initiation by inducing chromosomal instability. Here, we discuss recent developments in our understanding of the role of telomeres in replication stress and how telomerase expression in somatic stem cells may affect genome integrity control and carcinogenesis.
Copyright © 2013 Elsevier Inc. All rights reserved.

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Year:  2013        PMID： 23374336     DOI： 10.1016/j.cell.2013.01.010

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  96 in total

Review 1.  How will telomeric complex be further contributed to our longevity? - the potential novel biomarkers of telomere complex counteracting both aging and cancer.

Authors:  Yiming Lu; Bohua Wei; Tao Zhang; Zi Chen; Jing Ye
Journal:  Protein Cell       Date:  2013-07-18       Impact factor: 14.870

Review 2.  The emerging role of triple helices in RNA biology.

Authors:  Nicholas K Conrad
Journal:  Wiley Interdiscip Rev RNA       Date:  2013-09-30       Impact factor: 9.957

Review 3.  Genomic Medicine and Implications for Hepatocellular Carcinoma Prevention and Therapy.

Authors:  Renumathy Dhanasekaran; Jean-Charles Nault; Lewis R Roberts; Jessica Zucman-Rossi
Journal:  Gastroenterology       Date:  2018-11-04       Impact factor: 22.682

Review 4.  Radiopharmaceuticals as probes to characterize tumour tissue.

Authors:  Israt S Alam; Mubarik A Arshad; Quang-Dé Nguyen; Eric O Aboagye
Journal:  Eur J Nucl Med Mol Imaging       Date:  2015-02-03       Impact factor: 9.236

Review 5.  TERT Promoter Mutations in Thyroid Cancer.

Authors:  Ali S Alzahrani; Rawan Alsaadi; Avaniyapuram Kannan Murugan; Bakr Bin Sadiq
Journal:  Horm Cancer       Date:  2016-02-22       Impact factor: 3.869

6.  Non-canonical NF-κB signalling and ETS1/2 cooperatively drive C250T mutant TERT promoter activation.

Authors:  Yinghui Li; Qi-Ling Zhou; Wenjie Sun; Prashant Chandrasekharan; Hui Shan Cheng; Zhe Ying; Manikandan Lakshmanan; Anandhkumar Raju; Daniel G Tenen; Shi-Yuan Cheng; Kai-Hsiang Chuang; Jun Li; Shyam Prabhakar; Mengfeng Li; Vinay Tergaonkar
Journal:  Nat Cell Biol       Date:  2015-09-21       Impact factor: 28.824

Review 7.  Alternative lengthening of telomeres phenotype and loss of ATRX expression in sarcomas.

Authors:  Xiaolei Ren; Chao Tu; Zhenchu Tang; Ruofei Ma; Zhihong Li
Journal:  Oncol Lett       Date:  2018-03-22       Impact factor: 2.967

Review 8.  Revisiting the hallmarks of cancer.

Authors:  Yousef Ahmed Fouad; Carmen Aanei
Journal:  Am J Cancer Res       Date:  2017-05-01       Impact factor: 6.166

9.  Mutant IDH1 Expression Drives TERT Promoter Reactivation as Part of the Cellular Transformation Process.

Authors:  Shigeo Ohba; Joydeep Mukherjee; Tor-Christian Johannessen; Andrew Mancini; Tracy T Chow; Matthew Wood; Lindsey Jones; Tali Mazor; Roxanne E Marshall; Pavithra Viswanath; Kyle M Walsh; Arie Perry; Robert J A Bell; Joanna J Phillips; Joseph F Costello; Sabrina M Ronen; Russell O Pieper
Journal:  Cancer Res       Date:  2016-10-06       Impact factor: 12.701

10.  Inactivating ARID1A Tumor Suppressor Enhances TERT Transcription and Maintains Telomere Length in Cancer Cells.

Authors:  Yohan Suryo Rahmanto; Jin-Gyoung Jung; Ren-Chin Wu; Yusuke Kobayashi; Christopher M Heaphy; Alan K Meeker; Tian-Li Wang; Ie-Ming Shih
Journal:  J Biol Chem       Date:  2016-03-07       Impact factor: 5.157
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