Literature DB >> 23372376

Posterior subtenon triamcinolone acetonide in gas-filled eyes as an adjunctive treatment for complicated proliferative diabetic retinopathy.

Yongeun Lee1, Seungbum Kang, Young-Hoon Park.   

Abstract

PURPOSE: To evaluate the effect of adjunctive subtenon injection of triamcinolone acetonide (TA) in gas-filled eyes after vitrectomy for complicated proliferative diabetic retinopathy (PDR).
METHODS: This nonrandomized comparative study included 27 patients (27 eyes) who underwent pars plana vitrectomy and gas tamponade for treatment of PDR with tractional or combined tractional-rhegmatogenous retinal detachment and who received subtenon injection of TA (40 mg) at the end of surgery. The study group was compared with the control group (29 eyes), which was matched with the study group for preoperative and intraoperative parameters, but underwent pars plana vitrectomy and gas tamponade without a subtenon injection of TA.
RESULTS: Retinal reattachments without reoperation were achieved in 25 eyes (92.6%) and 26 eyes (89.7%) at 6 months (p = 1.000) in the study and control groups, respectively. The study group and the control group did not differ significantly in the frequency of postoperative proliferative vitreoretinopathy, retinal redetachment rate, reoperation rate, macular pucker formation, postoperative vitreous hemorrhage, gain in visual acuity, intraocular pressure, and intraocular inflammation (p > 0.05).
CONCLUSIONS: The clinical results of pars plana vitrectomy for complicated PDR are not improved significantly by an adjunctive subtenon TA injection in gas-filled eyes.

Entities:  

Keywords:  Gas tamponade; Pars plana vitrectomy; Posterior subtenon injection; Proliferative diabetic retinopathy; Triamcinolone acetonide

Mesh:

Substances:

Year:  2013        PMID: 23372376      PMCID: PMC3550308          DOI: 10.3341/kjo.2013.27.1.28

Source DB:  PubMed          Journal:  Korean J Ophthalmol        ISSN: 1011-8942


  41 in total

1.  Intravitreal triamcinolone for treatment of complicated proliferative diabetic retinopathy and proliferative vitreoretinopathy.

Authors:  Wuqaas M Munir; Jose S Pulido; Mithlesh C Sharma; Bruce M Buerk
Journal:  Can J Ophthalmol       Date:  2005-10       Impact factor: 1.882

Review 2.  Intravitreal triamcinolone acetonide for treatment of intraocular proliferative, exudative, and neovascular diseases.

Authors:  Jost B Jonas; Ingrid Kreissig; Robert Degenring
Journal:  Prog Retin Eye Res       Date:  2005-03-29       Impact factor: 21.198

3.  Posterior sub-Tenon's steroid injections for the treatment of posterior ocular inflammation: indications, efficacy and side effects.

Authors:  M Lafranco Dafflon; V T Tran; Y Guex-Crosier; C P Herbort
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1999-04       Impact factor: 3.117

4.  Regression of neovascular iris vessels by intravitreal injection of crystalline cortisone.

Authors:  J B Jonas; J K Hayler; A Söfker; S Panda-Jonas
Journal:  J Glaucoma       Date:  2001-08       Impact factor: 2.503

5.  Intraocular pressure elevation after intravitreal triamcinolone acetonide injection.

Authors:  Jost B Jonas; Robert F Degenring; Ingrid Kreissig; Imren Akkoyun; Bernd A Kamppeter
Journal:  Ophthalmology       Date:  2005-04       Impact factor: 12.079

6.  Intraocular injection of crystalline cortisone as adjunctive treatment of diabetic macular edema.

Authors:  J B Jonas; A Söfker
Journal:  Am J Ophthalmol       Date:  2001-09       Impact factor: 5.258

7.  Intravitreal triamcinolone-induced elevated intraocular pressure is associated with the development of posterior subcapsular cataract.

Authors:  Mark C Gillies; Maciek Kuzniarz; Jamie Craig; Matthew Ball; Wei Luo; Judy M Simpson
Journal:  Ophthalmology       Date:  2005-01       Impact factor: 12.079

8.  Triamcinolone-assisted pars plana vitrectomy improves the surgical procedures and decreases the postoperative blood-ocular barrier breakdown.

Authors:  Taiji Sakamoto; Miho Miyazaki; Toshio Hisatomi; Takao Nakamura; Akifumi Ueno; Keiko Itaya; Tatsuro Ishibashi
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2002-03-15       Impact factor: 3.117

9.  Safety of an intravitreal injection of triamcinolone: results from a randomized clinical trial.

Authors:  Mark C Gillies; Judy M Simpson; Frank A Billson; Wei Luo; Philip Penfold; William Chua; Paul Mitchell; Meidong Zhu; Alex B L Hunyor
Journal:  Arch Ophthalmol       Date:  2004-03

10.  Localization and quantitation of blood-retinal barrier breakdown in experimental proliferative vitreoretinopathy.

Authors:  N Ando; H A Sen; B A Berkowitz; C A Wilson; E de Juan
Journal:  Arch Ophthalmol       Date:  1994-01
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