Literature DB >> 23371284

The economic burden of alcohol dependence in Europe.

Philippe Laramée1, Jeanette Kusel, Saoirse Leonard, Henri-Jean Aubin, Clément François, Jean-Bernard Daeppen.   

Abstract

AIMS: To determine the economic burden pertaining to alcohol dependence in Europe.
METHODS: Database searching was combined with grey literature searching to identify costs and resource use in Europe relating to alcohol dependence as defined by the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) or the World Health Organisation's International Classification of Diseases (ICD-10). Searches combined MeSH headings for both economic terms and terms pertaining to alcohol dependence. Relevant outcomes included direct healthcare costs and indirect societal costs. Main resource use outcomes included hospitalization and drug costs.
RESULTS: Compared with the number of studies of the burden of alcohol use disorders in general, relatively few focussed specifically on alcohol dependence. Twenty-two studies of variable quality were eligible for inclusion. The direct costs of alcohol dependence in Europe were substantial, the treatment costs for a single alcohol-dependent patient lying within the range €1591-€7702 per hospitalization and the annual total direct costs accounting for 0.04-0.31% of an individual country's gross domestic product (GDP). These costs were driven primarily by hospitalization; in contrast, the annual drug costs for alcohol dependence were low. The indirect costs were more substantial than the direct costs, accounting for up to 0.64% of GDP per country annually. Alcohol dependence may be more costly in terms of health costs per patient than alcohol abuse.
CONCLUSIONS: This review confirms that alcohol dependence represents a significant burden for European healthcare systems and society. Difficulties in comparing across cost-of-illness studies in this disease area, however, prevent specific estimation of the economic burden.

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Year:  2013        PMID: 23371284     DOI: 10.1093/alcalc/agt004

Source DB:  PubMed          Journal:  Alcohol Alcohol        ISSN: 0735-0414            Impact factor:   2.826


  19 in total

1.  Dietary fat sources differentially modulate intestinal barrier and hepatic inflammation in alcohol-induced liver injury in rats.

Authors:  Wei Zhong; Qiong Li; Guoxiang Xie; Xiuhua Sun; Xiaobing Tan; Xinguo Sun; Wei Jia; Zhanxiang Zhou
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2013-10-10       Impact factor: 4.052

2.  The Cost Effectiveness of Nalmefene for Reduction of Alcohol Consumption in Alcohol-Dependent Patients with High or Very High Drinking-Risk Levels from a UK Societal Perspective.

Authors:  Thor-Henrik Brodtkorb; Melissa Bell; Adam H Irving; Philippe Laramée
Journal:  CNS Drugs       Date:  2016-02       Impact factor: 5.749

3.  Grey matter structural differences in alcohol-dependent individuals with and without comorbid depression/anxiety-an MRI study.

Authors:  A Uhlmann; B Bandelow; D J Stein; S Bloch; K R Engel; U Havemann-Reinecke; Dirk Wedekind
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2018-01-25       Impact factor: 5.270

4.  Alcohol Dependence, Co-occurring Conditions and Attributable Burden.

Authors:  B L Odlaug; A Gual; J DeCourcy; R Perry; J Pike; L Heron; J Rehm
Journal:  Alcohol Alcohol       Date:  2015-08-04       Impact factor: 2.826

5.  Modelling the consequences of a reduction in alcohol consumption among patients with alcohol dependence based on real-life observational data.

Authors:  Nora Rahhali; Aurélie Millier; Benjamin Briquet; Philippe Laramée; Samuel Aballéa; Mondher Toumi; Clément François; Jürgen Rehm; Jean-Bernard Daeppen
Journal:  BMC Public Health       Date:  2015-12-21       Impact factor: 3.295

6.  Distinct behavioral phenotypes in ethanol-induced place preference are associated with different extinction and reinstatement but not behavioral sensitization responses.

Authors:  João V N Pildervasser; Karina P Abrahao; Maria L O Souza-Formigoni
Journal:  Front Behav Neurosci       Date:  2014-08-08       Impact factor: 3.558

Review 7.  Multidisciplinary View of Alcohol Use Disorder: From a Psychiatric Illness to a Major Liver Disease.

Authors:  Stefano Gitto; Lucia Golfieri; Fabio Caputo; Silvana Grandi; Pietro Andreone
Journal:  Biomolecules       Date:  2016-01-15

8.  Protective Effects of Ecklonia stolonifera Extract on Ethanol-Induced Fatty Liver in Rats.

Authors:  Chae-Young Bang; Jae-Hyuk Byun; Hye-Kyung Choi; Jae-Sue Choi; Se-Young Choung
Journal:  Biomol Ther (Seoul)       Date:  2016-11-01       Impact factor: 4.634

Review 9.  Cognitive impairments in alcohol-dependent subjects.

Authors:  Florent Bernardin; Anne Maheut-Bosser; François Paille
Journal:  Front Psychiatry       Date:  2014-07-16       Impact factor: 4.157

10.  Economic burden associated with alcohol dependence in a German primary care sample: a bottom-up study.

Authors:  Jakob Manthey; Philippe Laramée; Steve Parrott; Jürgen Rehm
Journal:  BMC Public Health       Date:  2016-08-31       Impact factor: 3.295

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