Literature DB >> 23370997

The use of Integra® Dermal Regeneration Template in the reconstruction of traumatic degloving injuries.

G Peter Graham1, Stephen D Helmer, James M Haan, Anjay Khandelwal.   

Abstract

Traumatic soft tissue, or "degloving" injuries from trauma are common. These injuries are a result of shearing and disrupt tissue planes, such as the junction between muscle and bone. Traditional repair involves debridement followed by skin grafting or flap reconstruction. Many degloving injuries, however, extend to bone or tendon and the decreased vascularity of the wound bed can compromise the success of traditional repairs. Additionally, medical comorbidities make some patients poor candidates for flap reconstruction. The purpose of this study was to evaluate the success of a dermal regeneration template in the treatment of complex traumatic degloving injuries at an American College of Surgeons verified Level 1 Trauma Center. A retrospective review was conducted on all patients sustaining traumatic degloving injuries from January 2009 to July 2010, who were treated with Integra Dermal Regeneration Template followed by split-thickness autografting. Medical records were reviewed and patient demographics, injury characteristics, comorbidities, hospital course, and outcomes were summarized. Ten patients were studied. All had traumatic degloving injuries of an extremity ranging from 50 to 1000 cm. Nine had injuries extending to bone and/or tendon. After debridement, patients underwent placement of Integra followed by a split-thickness skin graft. Of the 10 patients nine had complete take of their grafts with excellent cosmetic and functional results. Degloving injuries are common in trauma. These injuries often extend to tendon and bone, which poses challenges to repair because of decreased vascularity. Placement of a dermal regeneration template followed by a split-thickness autograft is a viable alternative to traditional methods of repair.

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Year:  2013        PMID: 23370997     DOI: 10.1097/BCR.0b013e3182853eaf

Source DB:  PubMed          Journal:  J Burn Care Res        ISSN: 1559-047X            Impact factor:   1.845


  10 in total

1.  Integra® dermal regenerative template application on exposed tendon.

Authors:  John Hulsen; Ryan Diederich; Michael W Neumeister; Reuben A Bueno
Journal:  Hand (N Y)       Date:  2014-12

2.  Degloving Soft Tissue Injuries of the Extremity: Characterization, Categorization, Outcomes, and Management.

Authors:  Christine Velazquez; Litton Whitaker; Ivo A Pestana
Journal:  Plast Reconstr Surg Glob Open       Date:  2020-11-23

3.  In Situ Quantification of Surface Chemistry in Porous Collagen Biomaterials.

Authors:  Dimitrios S Tzeranis; Eric C Soller; Melissa C Buydash; Peter T C So; Ioannis V Yannas
Journal:  Ann Biomed Eng       Date:  2015-09-14       Impact factor: 3.934

Review 4.  Dermal skin substitutes for upper limb reconstruction: current status, indications, and contraindications.

Authors:  Shady A Rehim; Maneesh Singhal; Kevin C Chung
Journal:  Hand Clin       Date:  2014-05       Impact factor: 1.907

5.  Outcomes and Predictors of Wound Healing among Patients with Complex Diabetic Foot Wounds Treated with a Dermal Regeneration Template (Integra).

Authors:  Caitlin W Hicks; George Q Zhang; Joseph K Canner; Nestoras Mathioudakis; Devin Coon; Ronald L Sherman; Christopher J Abularrage
Journal:  Plast Reconstr Surg       Date:  2020-10       Impact factor: 5.169

Review 6.  Immune Cell Therapies to Improve Regeneration and Revascularization of Non-Healing Wounds.

Authors:  Elena Groppa; Andrea Colliva; Roman Vuerich; Tea Kocijan; Serena Zacchigna
Journal:  Int J Mol Sci       Date:  2020-07-23       Impact factor: 5.923

7.  Neutrophil Elastase Inhibitor Increases Flap Survival in Experimental Degloving Injuries.

Authors:  Erkan Yuce; Kamuran Zeynep Sevim; Medeni Volkan Kiyak; Kemalettin Yildiz; Daghan Dagdelen; Fatih Irmak; Semra Karsidag; Ulkan Kilic
Journal:  Sisli Etfal Hastan Tip Bul       Date:  2018-07-25

8.  Combination of negative pressure wound therapy (NPWT) and integra dermal regeneration template (IDRT) in the lower extremity wound; Our experience with 4 cases.

Authors:  Attia Attia; Tarek Elmenoufy; Tarek Atta; Ahmed Harfoush; Sayed Tarek
Journal:  JPRAS Open       Date:  2020-04-08

9.  Reconstruction of traumatic defect of the lower third of the leg using a combined therapy: negative pressure wound therapy, acellular dermal matrix, and skin graft.

Authors:  Sergio Brongo; Domenico Pagliara; Nicola Campitiello; Corrado Rubino
Journal:  Case Rep Surg       Date:  2014-08-11

10.  Comparative Effectiveness Analysis of Complex Lower Extremity Reconstruction: Outcomes and Costs for Biologically Based, Local Tissue Rearrangement, and Free Flap Reconstruction.

Authors:  Geoffrey M Kozak; Jesse Y Hsu; Robyn B Broach; Sameer Shakir; Catherine Calvert; John T Stranix; Charles Messa; L Scott Levin; Joseph M Serletti; Stephen J Kovach; John P Fischer
Journal:  Plast Reconstr Surg       Date:  2020-03       Impact factor: 5.169

  10 in total

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