Literature DB >> 23370959

Survival from profound metabolic acidosis due to hypovolaemic shock. A world record?

Nicola Di Rollo1, David Caesar, David A Ferenbach, Mark J G Dunn.   

Abstract

This case describes the unexpected survival of an adult man who presented to the emergency department with hypovolaemic shock secondary to a splenic haemorrhage. Before surgery he had a pH 6.527, base excess (BE) -34.2 mmol/l and lactate 15.6 mmol/l. He underwent a splenectomy after which his condition stabilised. He was managed in the intensive care unit postoperatively where he required organ support including renal replacement therapy but was subsequently discharged home with no neurological or renal deficit. Although there are case reports of patients surviving such profound metabolic acidosis these have mainly been cases of near drowning or toxic alcohol ingestion. To the best of our knowledge this is the first reported case of survival after a pH of 6.5 secondary to hypovolaemic shock.

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Year:  2013        PMID: 23370959      PMCID: PMC3603776          DOI: 10.1136/bcr-2012-008315

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  5 in total

1.  Hyperchloremic metabolic acidosis is a predictable consequence of intraoperative infusion of 0.9% saline.

Authors:  D S Prough; A Bidani
Journal:  Anesthesiology       Date:  1999-05       Impact factor: 7.892

2.  [Is it possible to survive metabolic acidosis with pH measure below 6.8? A study of two cases of inedible alcohol intoxication].

Authors:  Halina Kostek; Anna Kujawa; Jarosław Szponar; Piotr Danielewicz; Magdalena Majewska; Grzegorz Drelich
Journal:  Przegl Lek       Date:  2011

3.  [Extremely severe metabolic acidosis and multi-organ complications in ethylene glycol intoxication: a case study].

Authors:  Anna Kujawa; Halina Kostek; Jarosław Szponar; Magdalena Majewska; Beata Ossowska
Journal:  Przegl Lek       Date:  2011

4.  Survival put to the acid test: extreme arterial blood acidosis (pH 6.33) after near drowning.

Authors:  H Opdahl
Journal:  Crit Care Med       Date:  1997-08       Impact factor: 7.598

5.  Causes and effects of hyperchloremic acidosis.

Authors:  Michael Eisenhut
Journal:  Crit Care       Date:  2006-06-29       Impact factor: 9.097

  5 in total
  3 in total

1.  Recovery from profound acidosis (pH 6.685) in multi-organ dysfunction syndrome.

Authors:  Eryl A Davies; Christopher Saleh; Jonathan Bannard-Smith
Journal:  J Intensive Care Soc       Date:  2019-09-05

2.  Effects of metabolic acidosis on intracellular pH responses in multiple cell types.

Authors:  Ahlam Ibrahim Salameh; Vernon A Ruffin; Walter F Boron
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2014-09-10       Impact factor: 3.619

3.  The role of acid-base imbalance in statin-induced myotoxicity.

Authors:  Dhiaa A Taha; Cornelia H De Moor; David A Barrett; Jong Bong Lee; Raj D Gandhi; Chee Wei Hoo; Pavel Gershkovich
Journal:  Transl Res       Date:  2016-03-29       Impact factor: 7.012

  3 in total

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