OBJECTIVE: To document the effect of intratympanic gentamicin as treatment of disabling vertigo secondary to a vestibular schwannoma in elderly patients. PATIENTS: Four elderly patients with a vestibular schwannoma, with an extrameatal diameter of less than 1 cm, experiencing disabling vertigo and followed a wait-and-scan policy. INTERVENTION: Intratympanic injection of gentamicin. MAIN OUTCOME MEASURES: Subjective improvement of quality of life and audiologic and vestibular assessment. RESULTS: We obtained a subjective improvement in the quality of life for all the 4 patients. In fact, disabling vertigo disappeared in all cases; 3 patients recovered their posttreatment unsteadiness after a period of vestibular rehabilitation, whereas one of them complained of persistent unsteadiness. The hearing remained unchanged in 3 patients, whereas in one, the pretreatment severe sensorineural hearing loss progressed to anacusis. CONCLUSION: This treatment represents an additional option in patients with small not-growing tumor affected by vestibular symptoms to be combined with a wait-and-scan policy.
OBJECTIVE: To document the effect of intratympanic gentamicin as treatment of disabling vertigo secondary to a vestibular schwannoma in elderly patients. PATIENTS: Four elderly patients with a vestibular schwannoma, with an extrameatal diameter of less than 1 cm, experiencing disabling vertigo and followed a wait-and-scan policy. INTERVENTION: Intratympanic injection of gentamicin. MAIN OUTCOME MEASURES: Subjective improvement of quality of life and audiologic and vestibular assessment. RESULTS: We obtained a subjective improvement in the quality of life for all the 4 patients. In fact, disabling vertigo disappeared in all cases; 3 patients recovered their posttreatment unsteadiness after a period of vestibular rehabilitation, whereas one of them complained of persistent unsteadiness. The hearing remained unchanged in 3 patients, whereas in one, the pretreatment severe sensorineural hearing loss progressed to anacusis. CONCLUSION: This treatment represents an additional option in patients with small not-growing tumor affected by vestibular symptoms to be combined with a wait-and-scan policy.
Authors: Catherine M Kelso; Hirobumi Watanabe; Joseph M Wazen; Tizian Bucher; Zhen J Qian; Elizabeth S Olson; Jeffrey W Kysar; Anil K Lalwani Journal: Otol Neurotol Date: 2015-04 Impact factor: 2.311
Authors: Jan Betka; Eduard Zvěřina; Zuzana Balogová; Oliver Profant; Jiří Skřivan; Josef Kraus; Jiří Lisý; Josef Syka; Martin Chovanec Journal: Biomed Res Int Date: 2014-05-28 Impact factor: 3.411
Authors: Alexander A Tarnutzer; Christopher J Bockisch; Elena Buffone; Alexander M Huber; Vincent G Wettstein; Konrad P Weber Journal: Front Neurol Date: 2021-02-09 Impact factor: 4.003