BACKGROUND: The assessment of the impact aerobic exercises on bone mineral density in breast cancer women during endocrine therapy (ET). MATERIAL/ METHODS: The study included 53 women (mean 44.3 ±SD 4.9) during breast cancer treatment. This was a nonrandomized, prospective clinical study. The following examinations of the assessment of bone in the DEXA were measured: the bone mineral density of the neck of a femur (FN), lumbar region L₁-L₄, and total body (TB) as well as defining of T-score and Z-score. The examinations were conducted for all the patients according to the schedule: before the beginning of ET, after 6 months of ET and after 12 months of ET (after 6 month aerobic training). RESULTS: After the first 6 months of ET without regular physical exercise the following results were noted: the BMD mean value of FN, in the L₁-L₄ spine region and in TB were significant lower than the initial value. After 6 month aerobic training, in the 12th month of the follow up, the BMD mean value of FN was 1.1% (p>0.05) lower, while in the L₁-L₄ spine region it was 5.6% (p<0.05) lower, and in TB 2.7% (p<0.05) lower in comparison to the values in the sixth month of the observation. CONCLUSIONS: That even short course of ET is related to changes in bone mineral density. The introduction of aerobic exercises caused a slowdown in negative changes in bones.
BACKGROUND: The assessment of the impact aerobic exercises on bone mineral density in breast cancerwomen during endocrine therapy (ET). MATERIAL/ METHODS: The study included 53 women (mean 44.3 ±SD 4.9) during breast cancer treatment. This was a nonrandomized, prospective clinical study. The following examinations of the assessment of bone in the DEXA were measured: the bone mineral density of the neck of a femur (FN), lumbar region L₁-L₄, and total body (TB) as well as defining of T-score and Z-score. The examinations were conducted for all the patients according to the schedule: before the beginning of ET, after 6 months of ET and after 12 months of ET (after 6 month aerobic training). RESULTS: After the first 6 months of ET without regular physical exercise the following results were noted: the BMD mean value of FN, in the L₁-L₄ spine region and in TB were significant lower than the initial value. After 6 month aerobic training, in the 12th month of the follow up, the BMD mean value of FN was 1.1% (p>0.05) lower, while in the L₁-L₄ spine region it was 5.6% (p<0.05) lower, and in TB 2.7% (p<0.05) lower in comparison to the values in the sixth month of the observation. CONCLUSIONS: That even short course of ET is related to changes in bone mineral density. The introduction of aerobic exercises caused a slowdown in negative changes in bones.
Authors: Robson Chacon Castoldi; Guilherme Akio Tamura Ozaki; Thiago Alves Garcia; Ines Cristina Giometti; Tatiana Emy Koike; Regina Celi Trindade Camargo; João Domingos Augusto Dos Santos Pereira; Carlos José Leopoldo Constantino; Mário Jefferson Quirino Louzada; José Carlos Silva Camargo Filho; William Dias Belangero Journal: Lasers Med Sci Date: 2019-06-15 Impact factor: 3.161