Literature DB >> 23368268

Actively stressed marginal networks.

M Sheinman1, C P Broedersz, F C MacKintosh.   

Abstract

We study the effects of motor-generated stresses in disordered three-dimensional fiber networks using a combination of a mean-field theory, scaling analysis, and a computational model. We find that motor activity controls the elasticity in an anomalous fashion close to the point of marginal stability by coupling to critical network fluctuations. We also show that motor stresses can stabilize initially floppy networks, extending the range of critical behavior to a broad regime of network connectivities below the marginal point. Away from this regime, or at high stress, motors give rise to a linear increase in stiffness with stress. Finally, we demonstrate that our results are captured by a simple, constitutive scaling relation highlighting the important role of nonaffine strain fluctuations as a susceptibility to motor stress.

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Year:  2012        PMID: 23368268     DOI: 10.1103/PhysRevLett.109.238101

Source DB:  PubMed          Journal:  Phys Rev Lett        ISSN: 0031-9007            Impact factor:   9.161


  8 in total

1.  Stress controls the mechanics of collagen networks.

Authors:  Albert James Licup; Stefan Münster; Abhinav Sharma; Michael Sheinman; Louise M Jawerth; Ben Fabry; David A Weitz; Fred C MacKintosh
Journal:  Proc Natl Acad Sci U S A       Date:  2015-07-20       Impact factor: 11.205

2.  Compression stiffening of fibrous networks with stiff inclusions.

Authors:  Jordan L Shivers; Jingchen Feng; Anne S G van Oosten; Herbert Levine; Paul A Janmey; Fred C MacKintosh
Journal:  Proc Natl Acad Sci U S A       Date:  2020-08-17       Impact factor: 11.205

3.  Active Prestress Leads to an Apparent Stiffening of Cells through Geometrical Effects.

Authors:  Elisabeth Fischer-Friedrich
Journal:  Biophys J       Date:  2018-01-23       Impact factor: 4.033

Review 4.  Effects of non-linearity on cell-ECM interactions.

Authors:  Qi Wen; Paul A Janmey
Journal:  Exp Cell Res       Date:  2013-06-05       Impact factor: 3.905

5.  Uncoupling shear and uniaxial elastic moduli of semiflexible biopolymer networks: compression-softening and stretch-stiffening.

Authors:  Anne S G van Oosten; Mahsa Vahabi; Albert J Licup; Abhinav Sharma; Peter A Galie; Fred C MacKintosh; Paul A Janmey
Journal:  Sci Rep       Date:  2016-01-13       Impact factor: 4.379

6.  Self-organized stress patterns drive state transitions in actin cortices.

Authors:  Tzer Han Tan; Maya Malik-Garbi; Enas Abu-Shah; Junang Li; Abhinav Sharma; Fred C MacKintosh; Kinneret Keren; Christoph F Schmidt; Nikta Fakhri
Journal:  Sci Adv       Date:  2018-06-06       Impact factor: 14.136

7.  Cytoskeletal stiffening in synthetic hydrogels.

Authors:  Paula de Almeida; Maarten Jaspers; Sarah Vaessen; Oya Tagit; Giuseppe Portale; Alan E Rowan; Paul H J Kouwer
Journal:  Nat Commun       Date:  2019-02-05       Impact factor: 14.919

8.  Modeling myosin Va liposome transport through actin filament networks reveals a percolation threshold that modulates transport properties.

Authors:  S Walcott; D M Warshaw
Journal:  Mol Biol Cell       Date:  2021-12-22       Impact factor: 3.612

  8 in total

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