Literature DB >> 23365165

Delayed diagnosis of cryptococcal meningoencephalitis due to negative cryptococcal antigen test.

Bernhard Kessler1, Frank Bally, Ekkehard Hewer, Parham Sendi.   

Abstract

Cryptococcus spp. commonly causes infection in immunocompromised hosts. Clinical presentation of cryptococcal meningoencephalitis (CM) is variable, but headache, fever and a high intracranial pressure should suggest the diagnosis. The cryptococcal antigen test is a specific and sensitive rapid test that can be performed on blood or cerebrospinal fluid. We report a case of CM in a patient with previously undetected lymphocytopenia. Because cryptococcal antigen test results were negative, diagnosis and treatment were delayed.

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Year:  2013        PMID： 23365165      PMCID： PMC3604552          DOI： 10.1136/bcr-2012-007980

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN： 1757-790X


  8 in total

1.  Cryptococcus gattii infection in healthy hosts: a sentinel for subclinical immunodeficiency?

Authors:  Kieren A Marr; Kausik Datta; Liise-anne Pirofski; Robert Barnes
Journal:  Clin Infect Dis       Date:  2011-11-10       Impact factor: 9.079

2.  Cryptococcosis in human immunodeficiency virus-negative patients in the era of effective azole therapy.

Authors:  P G Pappas; J R Perfect; G A Cloud; R A Larsen; G A Pankey; D J Lancaster; H Henderson; C A Kauffman; D W Haas; M Saccente; R J Hamill; M S Holloway; R M Warren; W E Dismukes
Journal:  Clin Infect Dis       Date:  2001-07-26       Impact factor: 9.079

3.  Idiopathic CD4+T-cell lymphocytopenia associated with vitiligo.

Authors:  Paul S Yamauchi; Nathalie Q Nguyen; Pearl E Grimes
Journal:  J Am Acad Dermatol       Date:  2002-05       Impact factor: 11.527

4.  Evaluation of a commercial enzyme immunoassay for the detection of cryptococcal antigen.

Authors:  A S Sekhon; A K Garg; L Kaufman; G S Kobayashi; Z Hamir; M Jalbert; N Moledina
Journal:  Mycoses       Date:  1993 Jan-Feb       Impact factor: 4.377

5.  Disseminated cryptococcosis in HIV-uninfected patients.

Authors:  Y-M Chuang; Y-C Ho; H-T Chang; C-J Yu; P-C Yang; P-R Hsueh
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2008-04       Impact factor: 3.267

6.  A prospective descriptive study of cryptococcal meningitis in HIV uninfected patients in Vietnam - high prevalence of Cryptococcus neoformans var grubii in the absence of underlying disease.

Authors:  Tran Th Chau; Nguyen H Mai; Nguyen H Phu; Ho D Nghia; Ly V Chuong; Dinh X Sinh; Van A Duong; Pham T Diep; James I Campbell; Stephen Baker; Tran T Hien; David G Lalloo; Jeremy J Farrar; Jeremy N Day
Journal:  BMC Infect Dis       Date:  2010-07-09       Impact factor: 3.090

7.  Comparison of commercial kits for detection of cryptococcal antigen.

Authors:  D C Tanner; M P Weinstein; B Fedorciw; K L Joho; J J Thorpe; L Reller
Journal:  J Clin Microbiol       Date:  1994-07       Impact factor: 5.948

Review 8.  Cryptococcal meningitis. False-negative antigen test results and cultures in nonimmunosuppressed patients.

Authors:  L Berlin; J H Pincus
Journal:  Arch Neurol       Date:  1989-12
  8 in total
  2 in total

1.  Cryptococcal Meningitis Presenting as New-Onset Seizures in an Immunocompetent Patient.

Authors:  Andrea Akyeampong; Nadia Solomon; Nicholas A Boire; Aam A Baqui
Journal:  J Investig Med High Impact Case Rep       Date:  2019 Jan-Dec

2.  Immune reconstitution inflammatory syndrome following Cryptococcal neoformans infection in an immunocompetent host: A case report and review of the literature.

Authors:  Raguharan Kathiresu; Syeda Nabila Zinat; Malindu Fernando
Journal:  IDCases       Date:  2020-01-09
  2 in total

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