Literature DB >> 23364596

The expanding genetic toolkit for exploring mechanisms of general anesthesia.

Stuart A Forman.   

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Year:  2013        PMID: 23364596      PMCID: PMC3680125          DOI: 10.1097/ALN.0b013e318287b7e4

Source DB:  PubMed          Journal:  Anesthesiology        ISSN: 0003-3022            Impact factor:   7.892


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  14 in total

1.  General anesthetic actions in vivo strongly attenuated by a point mutation in the GABA(A) receptor beta3 subunit.

Authors:  Rachel Jurd; Margarete Arras; Sachar Lambert; Berthold Drexler; Roberta Siegwart; Florence Crestani; Michael Zaugg; Kaspar E Vogt; Birgit Ledermann; Bernd Antkowiak; Uwe Rudolph
Journal:  FASEB J       Date:  2002-12-03       Impact factor: 5.191

2.  Effect of N-methyl-D-aspartate receptor epsilon1 subunit gene disruption of the action of general anesthetic drugs in mice.

Authors:  Yuki Sato; Eiji Kobayashi; Takanori Murayama; Masayoshi Mishina; Norimasa Seo
Journal:  Anesthesiology       Date:  2005-03       Impact factor: 7.892

3.  Optogenetics. Shining new light on neural circuits.

Authors:  Greg Miller
Journal:  Science       Date:  2006-12-15       Impact factor: 47.728

Review 4.  General anaesthesia: from molecular targets to neuronal pathways of sleep and arousal.

Authors:  Nicholas P Franks
Journal:  Nat Rev Neurosci       Date:  2008-05       Impact factor: 34.870

5.  Subunit-dependent interaction of the general anaesthetic etomidate with the gamma-aminobutyric acid type A receptor.

Authors:  C Hill-Venning; D Belelli; J A Peters; J J Lambert
Journal:  Br J Pharmacol       Date:  1997-03       Impact factor: 8.739

6.  R (+) etomidate and the photoactivable R (+) azietomidate have comparable anesthetic activity in wild-type mice and comparably decreased activity in mice with a N265M point mutation in the gamma-aminobutyric acid receptor beta3 subunit.

Authors:  Mark Liao; James M Sonner; S Shaukat Husain; Keith W Miller; Rachel Jurd; Uwe Rudolph; Edmond I Eger
Journal:  Anesth Analg       Date:  2005-07       Impact factor: 5.108

7.  Forebrain HCN1 channels contribute to hypnotic actions of ketamine.

Authors:  Cheng Zhou; Jennifer E Douglas; Natasha N Kumar; Shaofang Shu; Douglas A Bayliss; Xiangdong Chen
Journal:  Anesthesiology       Date:  2013-04       Impact factor: 7.892

Review 8.  Correlating the clinical actions and molecular mechanisms of general anesthetics.

Authors:  Ken Solt; Stuart A Forman
Journal:  Curr Opin Anaesthesiol       Date:  2007-08       Impact factor: 2.706

9.  HCN1 channel subunits are a molecular substrate for hypnotic actions of ketamine.

Authors:  Xiangdong Chen; Shaofang Shu; Douglas A Bayliss
Journal:  J Neurosci       Date:  2009-01-21       Impact factor: 6.167

10.  New insight into the role of the beta3 subunit of the GABAA-R in development, behavior, body weight regulation, and anesthesia revealed by conditional gene knockout.

Authors:  Carolyn Ferguson; Steven L Hardy; David F Werner; Stanley M Hileman; Timothy M Delorey; Gregg E Homanics
Journal:  BMC Neurosci       Date:  2007-10-10       Impact factor: 3.288

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