BACKGROUND AND AIMS: Both personality changes and behavioural and psychological symptoms (BPS) may be associated with mild cognitive impairment (MCI) in later life and help identify incipient dementia. We wished to investigate the links between personality and BPS in MCI. METHOD: We studied premorbid personality traits as estimated 5 years back and their changes in 83 control subjects and 52 MCI patients using the revised NEO Personality Inventory for the Five-Factor Model completed by a proxy. Information on BPS was obtained using the Neuropsychiatric Inventory (NPI). Analyses were controlled for current depression and anxiety. RESULTS: Premorbid neuroticism and openness to experience were associated with the total NPI score. The changes in neuroticism, extraversion, openness to experiences, and conscientiousness were associated with apathy and affective symptoms. CONCLUSIONS: Personality changes and BPS occur in MCI. The occurrence of affective BPS and apathy is associated with both premorbid personality traits and their changes.
BACKGROUND AND AIMS: Both personality changes and behavioural and psychological symptoms (BPS) may be associated with mild cognitive impairment (MCI) in later life and help identify incipient dementia. We wished to investigate the links between personality and BPS in MCI. METHOD: We studied premorbid personality traits as estimated 5 years back and their changes in 83 control subjects and 52 MCI patients using the revised NEO Personality Inventory for the Five-Factor Model completed by a proxy. Information on BPS was obtained using the Neuropsychiatric Inventory (NPI). Analyses were controlled for current depression and anxiety. RESULTS:Premorbid neuroticism and openness to experience were associated with the total NPI score. The changes in neuroticism, extraversion, openness to experiences, and conscientiousness were associated with apathy and affective symptoms. CONCLUSIONS: Personality changes and BPS occur in MCI. The occurrence of affective BPS and apathy is associated with both premorbid personality traits and their changes.
Authors: Maheen Islam; Mridul Mazumder; Derek Schwabe-Warf; Yannick Stephan; Angelina R Sutin; Antonio Terracciano Journal: J Am Med Dir Assoc Date: 2019-01-07 Impact factor: 4.669
Authors: Tomiko Yoneda; Eileen Graham; Tristen Lozinski; David A Bennett; Daniel Mroczek; Andrea M Piccinin; Scott M Hofer; Graciela Muniz-Terrera Journal: J Pers Soc Psychol Date: 2022-04-11
Authors: Angelina R Sutin; Yannick Stephan; Martina Luchetti; Antonio Terracciano Journal: Int J Geriatr Psychiatry Date: 2017-09-04 Impact factor: 3.485
Authors: Andrew J Aschenbrenner; Jennifer Petros; Eric McDade; Guoqiao Wang; David A Balota; Tammie Ls Benzinger; Carlos Cruchaga; Alison Goate; Chengjie Xiong; Richard Perrin; Anne M Fagan; Neill Graff-Radford; Bernardino Ghetti; Johannes Levin; Endy Weidinger; Peter Schofield; Susanne Gräber; Jae-Hong Lee; Jasmeer P Chhatwal; John C Morris; Randall Bateman; Jason Hassenstab Journal: Alzheimers Dement (Amst) Date: 2020-06-23