Literature DB >> 23361274

Experimental and Monte Carlo study of the effect of the presence of dry air, cortical bone inhomogeneities and source position on dose distribution of the mHDR-v2 source.

Rakesh M Chandola1, Samit Tiwari, Manjula Beck, Pradeep Kumar Chandrakar, Suresh Kumar Thakur.   

Abstract

BACKGROUND: Recently it was data wise established that there is a considerable dose difference due to source position from the surface of the patient, and due to the presence of inhomogeneities. AIM: It aims at to find out the dose difference due to source position, and inhomogenieties in water phantom of high dose rate (HDR)(192) Ir mHDR-v2 source by experiment and by Monte Carlo (MC) simulation GEANT4 code.
MATERIALS AND METHODS: The measured study of the source was done using an in-air ionization chamber, water phantom while the calculated study was done by modeling the water phantom and its water, inhomogeneities, position of source, and points of calculation.
RESULTS: The measured and calculated dose differences are 5.48 to 6.46% and 5.43 to 6.44% respectively higher in the presence of dry air and 4.40 to 4.90% and 4.38 to 4.88% respectively lower in the presence of cortical bone. However, for the study of the effect of source position on dose distribution, when the source was positioned at a 1 cm distance from the surface of water phantom, the near points between 1 cm and 2 cm are 2 to 3.5% and 2.1-3.7% underdose and for distant points from 3 cm to 8 cm from the source are 4 to 15% and 4.1 to 15.8% underdose for measured and calculated studies, respectively, to the dose when the source was positioned at midpoint of water phantom.
CONCLUSION: These results can be used in the treatment planning system.

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Year:  2012        PMID: 23361274     DOI: 10.4103/0973-1482.106536

Source DB:  PubMed          Journal:  J Cancer Res Ther        ISSN: 1998-4138            Impact factor:   1.805


  1 in total

1.  Dosimetric analysis of Co-60 source based high dose rate (HDR) brachytherapy: A case series of ten patients with carcinoma of the uterine cervix.

Authors:  Om Prakash Gurjar; Manika Batra; Priyusha Bagdare; Sandeep Kaushik; Atul Tyagi; Ayush Naik; Virendra Bhandari; Krishna Lal Gupta
Journal:  Rep Pract Oncol Radiother       Date:  2016-03-02
  1 in total

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