| Literature DB >> 23357362 |
Eugen J Verspohl1, Hajime Fujii, Kohei Homma, Sybille Buchwald-Werner.
Abstract
Gastrointestinal discomfort is frequently observed. The effects of Perilla frutescens extract and Vicenin 2 (a compound in this extract) were assayed in rat ileum with or without stimulation with acetylcholine or Ba(2+). Both had no direct spasmolytic effect, but both decreased acetylcholine- or Ba(2+)-induced contraction of rat ileum indicating an antispasmodic effect. This is valuable because effects were only observed when spasms were induced and may disturb the patient. The extract and the compound may be used to maintain and improve gut health.Entities:
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Year: 2013 PMID： 23357362 DOI： 10.1016/j.phymed.2012.12.018
Source DB: PubMed Journal: Phytomedicine ISSN： 0944-7113 Impact factor: 5.340