Literature DB >> 23354560

[Ex situ tracheobronchoplastic operations using the organ care system].

M Krüger1, N Zinne, H Höffler, R Zhang, I Kropivnitskaja, J Schmitto, A Ciubotaru, A Haverich.   

Abstract

First clinical experiences with the organ care system (OCS) in lung transplantation showed that this device allows perfusion and ventilation of the lungs under practically physiological conditions. Some pulmonary pathologies necessitate ex situ operations, e.g. to avoid pneumonectomy. The objective of this work was to investigate the feasibility of ex situ pulmonary surgery within the OCS.In the first procedure a large tracheobronchial leakage was covered with a pericardial patch. The procedure was authorized by the local committee of animal welfare. In the second surgery a replacement of the distal trachea using an aortic graft was performed after removal of the heart-lung segment from a pig from the slaughterhouse. The postoperative ventilation of both lungs was free of problems. The mean pressure of the pulmonary artery remained steady during the whole experiment. The setup to prevent lung edema was basically successful.Performing thoracic surgery with the OCS is feasible; however, this approach is reserved for very special indications. Further investigations to optimize technical details of the OCS setup for this purpose are necessary.

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Year:  2013        PMID: 23354560     DOI: 10.1007/s00104-012-2444-1

Source DB:  PubMed          Journal:  Chirurg        ISSN: 0009-4722            Impact factor:   0.955


  13 in total

1.  [Ex situ sleeve resection and autotransplantation of the left lower pulmonary lobe after extended pneumonectomy].

Authors:  H Hendrix; J Schmitt; H Aebert
Journal:  Chirurg       Date:  2000-07       Impact factor: 0.955

2.  Long-term evaluation of the replacement of the trachea with an autologous aortic graft.

Authors:  Emmanuel Martinod; Agathe Seguin; Karel Pfeuty; Paul Fornes; Marianne Kambouchner; Jacques F Azorin; Alain F Carpentier
Journal:  Ann Thorac Surg       Date:  2003-05       Impact factor: 4.330

3.  Establishment of a porcine model for lobar lung auto-transplantation.

Authors:  B Ren; M Li; Z Hu; J Hu; F Jiang; R Ying; Z Zhang; L Xu
Journal:  Transplant Proc       Date:  2010-09       Impact factor: 1.066

4.  [Lung auto-transplantation technique in the treatment for stage III central lung cancer].

Authors:  Feng Jiang; Lin Xu; Fang-liang Yuan; Jian-feng Huang; Xin-xin Lu; Xiao-ying Zhang
Journal:  Zhonghua Yi Xue Za Zhi       Date:  2010-05-18

5.  Tracheal regeneration following tracheal replacement with an allogenic aorta.

Authors:  Emmanuel Martinod; Agathe Seguin; Muriel Holder-Espinasse; Marianne Kambouchner; Martine Duterque-Coquillaud; Jacques F Azorin; Alain F Carpentier
Journal:  Ann Thorac Surg       Date:  2005-03       Impact factor: 4.330

6.  Tracheal replacement with aortic allografts.

Authors:  Alain Wurtz; Henri Porte; Massimo Conti; Jacques Desbordes; Marie Christine Copin; Jacques Azorin; Emmanuel Martinod; Charles-Hugo Marquette
Journal:  N Engl J Med       Date:  2006-11-02       Impact factor: 91.245

7.  Use of the aortic homograft in the reconstruction of complex tracheobronchial tree injuries.

Authors:  A A Chahine; V Tam; R R Ricketts
Journal:  J Pediatr Surg       Date:  1999-05       Impact factor: 2.545

8.  Technical pearls for swine lung transplantation.

Authors:  Ashkan Karimi; Jessica A Cobb; Edward D Staples; Maher A Baz; Thomas M Beaver
Journal:  J Surg Res       Date:  2011-06-25       Impact factor: 2.192

Review 9.  Tracheal replacement with an aortic autograft.

Authors:  Jacques F Azorin; Francois Bertin; Emmanuel Martinod; Marc Laskar
Journal:  Eur J Cardiothorac Surg       Date:  2006-01-04       Impact factor: 4.191

10.  Experimental study of extracorporeal lung resection in dogs: ex situ sleeve resection and autotransplantation of the pulmonary lobe after extended pneumonectomy for central lung cancer.

Authors:  Isao Matsumoto; Makoto Oda; Yoshio Tsunezuka; Masaya Tamura; Kazuyuki Kawakami; Go Watanabe
Journal:  J Thorac Cardiovasc Surg       Date:  2004-05       Impact factor: 5.209

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