Literature DB >> 23354114

Total atlanto-odontoid joint arthroplasty system: a novel motion preservation device for atlantoaxial instability after odontoidectomy.

Xuan Cai1, Xijing He, Haopeng Li, Dong Wang.   

Abstract

STUDY
DESIGN: An in vitro biomechanical study.
OBJECTIVE: To determine the initial stability and function of a novel total atlanto-odontoid joint arthroplasty system (TAAS) in human cadaveric cervical spine models by comparing it with a conventional method. SUMMARY OF BACKGROUND DATA: Resection of the odontoid and anterior arch of the atlas results in atlantoaxial instability, which if left uncorrected may lead to severe neurological complications. Currently, such atlantoaxial instability is corrected by anterior and/or posterior atlantoaxial fusion. However, this results in considerable motion loss of the atlantoaxial complex.
METHODS: Flexibility tests were conducted on 24 human cadaveric craniocervical specimens in the following sequence: (1) intact, (2) after dissection of the atlantoaxial ligaments and odontoidectomy, (3) after the TAAS implantation, and (4) after Harms rigid fixation. Rotational angles of the C1-C2 segment were measured to study the immediate stability and function of the TAAS implantation compared with the intact and Harms rigid fixation.
RESULTS: Comparing the TAAS implantation to the intact state, the range of motion and neutral zone changed little in flexion, extension, and lateral bending but increased significantly in axial rotation (P < 0.001). Compared with Harms rigid fixation, the TAAS implantation significantly increased range of motion and neutral zone in all directions (P < 0.001).
CONCLUSION: We have designed the TAAS for correcting atlantoaxial instability arising from C1-C2 anterior decompression procedures. The unique aspect of the TAAS is that it restores, to a great extent, the C1-C2 motion that is lost during current stabilization procedures.

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Mesh:

Year:  2013        PMID: 23354114     DOI: 10.1097/BRS.0b013e318288052a

Source DB:  PubMed          Journal:  Spine (Phila Pa 1976)        ISSN: 0362-2436            Impact factor:   3.468


  5 in total

1.  Preclinical evaluation of a novel anterior non-fusion fixation device for atlantoaxial instability: an in vivo comparison study in a canine model.

Authors:  Xuan Cai; Xiaoqing Yi; Haopeng Li; Xijing He
Journal:  Eur Spine J       Date:  2019-02-13       Impact factor: 3.134

2.  In vivo primary and coupled segmental motions of the healthy female head-neck complex during dynamic head axial rotation.

Authors:  Runsheng Guo; Chaochao Zhou; Cong Wang; Tsung-Yuan Tsai; Yan Yu; Wei Wang; Guoan Li; Thomas Cha
Journal:  J Biomech       Date:  2021-05-11       Impact factor: 2.789

Review 3.  Giant cell tumor of axial vertebra: surgical experience of five cases and a review of the literature.

Authors:  Guojing Chen; Jing Li; Xiangdong Li; Hongbin Fan; Zheng Guo; Zhen Wang
Journal:  World J Surg Oncol       Date:  2015-02-18       Impact factor: 2.754

4.  Artificial atlantoaxial joint: Is it a possible option?

Authors:  Atul Goel
Journal:  J Craniovertebr Junction Spine       Date:  2015 Oct-Dec

5.  C1-C2 arthroplasty for craniovertebral junction instability: A preliminary proof of concept in human cadavers.

Authors:  Pravin Salunke; Madhivanan Karthigeyan; Manoj Kumar Kodigudla; Amey V Kelkar; Vijay K Goel
Journal:  J Craniovertebr Junction Spine       Date:  2022-06-13
  5 in total

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