Literature DB >> 2335376

Tumour necrosis factor (TNF alpha) in leishmaniasis. I. TNF alpha mediates host protection against cutaneous leishmaniasis.

F Y Liew1, C Parkinson, S Millott, A Severn, M Carrier.   

Abstract

Genetically resistant CBA mice developed significantly larger lesions to Leishmania major infection when they were injected with rabbit anti-tumour necrosis factor (TNF)-specific antibodies compared to control mice injected with normal rabbit immunoglobulin. BALB/c mice recovered from a previous infection following prophylactic sublethal irradiation also developed exacerbated lesions when treated with the anti-TNF antibody. Injection of TNF into the lesion of infected CBA mice significantly reduced the lesion development. Furthermore, TNF activates macrophages to kill Leishmania in vitro. These data demonstrate that TNF plays an important role in mediating host-protection against cutaneous leishmaniasis.

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Year:  1990        PMID： 2335376      PMCID： PMC1385631     

Source DB:  PubMed          Journal:  Immunology        ISSN： 0019-2805            Impact factor:   7.397


  21 in total

1.  Purification and physico-chemical characterization of rabbit tumor necrosis factor.

Authors:  M R Ruff; G E Gifford
Journal:  J Immunol       Date:  1980-10       Impact factor: 5.422

2.  Inhibition of murine malaria (Plasmodium chabaudi) in vivo by recombinant interferon-gamma or tumor necrosis factor, and its enhancement by butylated hydroxyanisole.

Authors:  I A Clark; N H Hunt; G A Butcher; W B Cowden
Journal:  J Immunol       Date:  1987-11-15       Impact factor: 5.422

3.  Antiviral effects of recombinant tumour necrosis factor in vitro.

Authors:  J Mestan; W Digel; S Mittnacht; H Hillen; D Blohm; A Möller; H Jacobsen; H Kirchner
Journal:  Nature       Date:  1986 Oct 30-Nov 5       Impact factor: 49.962

4.  Macrophage activation by interferon-gamma from host-protective T cells is inhibited by interleukin (IL)3 and IL4 produced by disease-promoting T cells in leishmaniasis.

Authors:  F Y Liew; S Millott; Y Li; R Lelchuk; W L Chan; H Ziltener
Journal:  Eur J Immunol       Date:  1989-07       Impact factor: 5.532

5.  Tumor necrosis factor (cachectin) as an essential mediator in murine cerebral malaria.

Authors:  G E Grau; L F Fajardo; P F Piguet; B Allet; P H Lambert; P Vassalli
Journal:  Science       Date:  1987-09-04       Impact factor: 47.728

6.  Prophylactic immunization against experimental leishmaniasis. III. Protection against fatal Leishmania tropica infection induced by irradiated promastigotes involves Lyt-1+2- T cells that do not mediate cutaneous DTH.

Authors:  F Y Liew; J G Howard; C Hale
Journal:  J Immunol       Date:  1984-01       Impact factor: 5.422

7.  Tumor necrosis factor is involved in the T cell-independent pathway of macrophage activation in scid mice.

Authors:  G J Bancroft; K C Sheehan; R D Schreiber; E R Unanue
Journal:  J Immunol       Date:  1989-07-01       Impact factor: 5.422

8.  Production of tumor necrosis factor during murine listeriosis.

Authors:  E A Havell
Journal:  J Immunol       Date:  1987-12-15       Impact factor: 5.422

9.  Tumour necrosis factors alpha and beta inhibit virus replication and synergize with interferons.

Authors:  G H Wong; D V Goeddel
Journal:  Nature       Date:  1986 Oct 30-Nov 5       Impact factor: 49.962

10.  Immunological regulation of experimental cutaneous leishmaniasis. III. Nature and significance of specific suppression of cell-mediated immunity in mice highly susceptible to Leishmania tropica.

Authors:  J G Howard; C Hale; F Y Liew
Journal:  J Exp Med       Date:  1980-09-01       Impact factor: 14.307
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  55 in total

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Journal:  Am J Pathol       Date:  2010-10-29       Impact factor: 4.307

2.  Leishmania infantum sterol 24-c-methyltransferase formulated with MPL-SE induces cross-protection against L. major infection.

Authors:  Yasuyuki Goto; Ajay Bhatia; Vanitha S Raman; Silvia E Z Vidal; Sylvie Bertholet; Rhea N Coler; Randall F Howard; Steven G Reed
Journal:  Vaccine       Date:  2009-03-09       Impact factor: 3.641

3.  In vivo modulation of the murine immune response to Francisella tularensis LVS by administration of anticytokine antibodies.

Authors:  D A Leiby; A H Fortier; R M Crawford; R D Schreiber; C A Nacy
Journal:  Infect Immun       Date:  1992-01       Impact factor: 3.441

4.  Association of a functional TNF variant with Plasmodium falciparum parasitaemia in a congolese population.

Authors:  T N Nguyen; S Baaklini; F Koukouikila-Koussounda; M Ndounga; M Torres; L Pradel; F Ntoumi; P Rihet
Journal:  Genes Immun       Date:  2017-07-13       Impact factor: 2.676

5.  A new multi-epitope peptide vaccine induces immune responses and protection against Leishmania infantum in BALB/c mice.

Authors:  Bahareh Vakili; Navid Nezafat; Bijan Zare; Nasrollah Erfani; Maryam Akbari; Younes Ghasemi; Mohammad Reza Rahbar; Gholam Reza Hatam
Journal:  Med Microbiol Immunol       Date:  2019-11-06       Impact factor: 3.402

6.  Pneumocystis carinii stimulates in vitro production of tumor necrosis factor-alpha by human macrophages.

Authors:  E Tamburrini; A De Luca; G Ventura; G Maiuro; A Siracusano; E Ortona; A Antinori
Journal:  Med Microbiol Immunol       Date:  1991       Impact factor: 3.402

7.  Electrospray encapsulation of toll-like receptor agonist resiquimod in polymer microparticles for the treatment of visceral leishmaniasis.

Authors:  Anthony D Duong; Sadhana Sharma; Kevin J Peine; Gaurav Gupta; Abhay R Satoskar; Eric M Bachelder; Barbra E Wyslouzil; Kristy M Ainslie
Journal:  Mol Pharm       Date:  2013-02-12       Impact factor: 4.939

8.  Characterization of the immunogenetic basis of ultraviolet-B light effects on contact hypersensitivity induction.

Authors:  I Kurimoto; J W Streilein
Journal:  Immunology       Date:  1994-03       Impact factor: 7.397

9.  Lutzomyia longipalpis salivary gland homogenate impairs cytokine production and costimulatory molecule expression on human monocytes and dendritic cells.

Authors:  Dirceu J Costa; Cecília Favali; Jorge Clarêncio; Lílian Afonso; Viviane Conceição; José Carlos Miranda; Richard G Titus; Jesus Valenzuela; Manoel Barral-Netto; Aldina Barral; Cláudia Ida Brodskyn
Journal:  Infect Immun       Date:  2004-03       Impact factor: 3.441

10.  Resistance of Leishmania (Viannia) braziliensis to nitric oxide: correlation with antimony therapy and TNF-alpha production.

Authors:  Anselmo S Souza; Angela Giudice; Júlia Mb Pereira; Luís H Guimarães; Amelia R de Jesus; Tatiana R de Moura; Mary E Wilson; Edgar M Carvalho; Roque P Almeida
Journal:  BMC Infect Dis       Date:  2010-07-15       Impact factor: 3.090
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