| Literature DB >> 23352823 |
Armin Lühr1, Marlen Priegnitz, Fine Fiedler, Nikolai Sobolevsky, Niels Bassler.
Abstract
In ion beam cancer therapy, range verification in patients using positron emission tomography (PET) requires the comparison of measured with simulated positron emitter yields. We found that (1) changes in modeling nuclear interactions strongly affected the positron emitter yields and that (2) Monte Carlo simulations with SHIELD-HIT10Areasonably matched the most abundant PET isotopes (11)C and (15)O. We observed an ion-energy (i.e., depth) dependence of the agreement between SHIELD-HIT10Aand measurement. Improved modeling requires more accurate measurements of cross-section values.Entities:
Keywords: Ion beam cancer therapy; Monte Carlo simulation; Nuclear fragmentation; PET nuclides; SHIELD-HIT10A
Mesh:
Year: 2013 PMID: 23352823 DOI: 10.1016/j.apradiso.2012.12.018
Source DB: PubMed Journal: Appl Radiat Isot ISSN: 0969-8043 Impact factor: 1.513