Literature DB >> 23351451

[Arthritis: an unusual and anticipatory clinical presentation of pediatric acute lymphoblastic leukemia. A case report].

Carolina Duarte-Salazar1, Concepción Guadalupe Santillán-Chapa, Garly Daniel González-Rosado, Norma Marín-Arriaga, José Eugenio Vázquez-Meraz.   

Abstract

BACKGROUND: Acute lymphoblastic leukemia initially shows osteoarticular manifestations. However, it is rare that it shows juvenile idiopathic arthritis (JIA) symptoms. CLINICAL CASE: A child with acute lymphoblastic leukemia initially misdiagnosed with malignant neoplasia and septic arthritis, and later on with juvenile idiopathic arthritis. The child had persistent articular pain and swelling despite treatment. Six months later, a full blood count revealed leukopenia and neutropenia with lymphocytosis. A bone marrow aspirate confirmed pre-B acute lymphoblastic leukemia with hypodyploidia.
CONCLUSION: This case initially showed typical signs of arthritis, and a diagnosis of acute lymphoblastic leukemia was ruled out, since the those clinical features and hematologic alterations characterizing this hematologic neoplasia.

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Year:  2012        PMID: 23351451

Source DB:  PubMed          Journal:  Cir Cir        ISSN: 0009-7411            Impact factor:   0.361


  2 in total

Review 1.  Extramedullary manifestations in acute lymphoblastic leukemia in children: a systematic review and guideline-based approach of treatment.

Authors:  Mahdi Shahriari; Nader Shakibazad; Sezaneh Haghpanah; Khadijeh Ghasemi
Journal:  Am J Blood Res       Date:  2020-12-15

2.  THE DIFFERENTIAL ALGORITHM BETWEEN RHEUMATOLOGIC AND MALIGN DISEASES.

Authors:  Arbnore Batalli Këpuska; Lidvana Spahiju; Ramush Bejiq; Rufadije Manqestena; Valbona Stavileci; Zana Ibraimi
Journal:  Mater Sociomed       Date:  2016-03-25
  2 in total

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