Literature DB >> 23350737

Chiral bicyclic tetramates as non-planar templates for chemical library synthesis.

Muhammad Anwar1, Mark G Moloney.   

Abstract

Chemoselective Dieckmann cyclization reactions may be used on oxazolidine and thiazolidine templates derived from various aldehydes to access bicyclic tetramates, which have potential as templates for chemical library construction. Bioassay against Staphylococcus aureus and Escherichia coli showed that these systems have little or no intrinsic antibacterial bioactivity.
© 2013 John Wiley & Sons A/S.

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Year:  2013        PMID: 23350737     DOI: 10.1111/cbdd.12110

Source DB:  PubMed          Journal:  Chem Biol Drug Des        ISSN: 1747-0277            Impact factor:   2.817


  1 in total

1.  Fused-Ring Oxazolopyrrolopyridopyrimidine Systems with Gram-Negative Activity.

Authors:  Yiyuan Chen; Jonathan G Moloney; Kirsten E Christensen; Mark G Moloney
Journal:  Antibiotics (Basel)       Date:  2017-01-13
  1 in total

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