Literature DB >> 23350353

Embryonal rhabdomyosarcoma of the female genital tract: 5 years' experience.

Reda Hemida1, Hosam Goda, El-Said Abdel-Hady, Rasha El-Ashry.   

Abstract

OBJECTIVES: To present our single institution experience with 10 cases of embryonal rhabdomyosarcoma diagnosed over 5 years.
METHODS: Retrospective analysis of the medical records of 10 patients. The initial presenting data as age, complains and staging were analyzed. Surgical interference of all cases was studied. The follow up data regarding survival and recurrences were analyzed.
RESULTS: The mean age at diagnosis was 4.3 years (range: 2-12). Six cases (60%) were subjected to "True Cut" biopsy and 4 cases (40%) were subjected to complete surgical excision of the tumor. All cases received chemotherapy. "Vincristine, Actinomycin D, Cyclophosphamide" combination was the most commonly used. Radiation therapy was used in 3 patients (30%) in the form of external beam radiation. The 5-year overall survival of our studied cases were 80%.
CONCLUSION: The recurrence rate of our retrospectively studied 10 cases of embryonal rhabdomyosarcoma of vagina and cervix was high (70%). However, five-year survival was 80%. Combined modality treatment is essential to improve prognosis.

Entities:  

Mesh:

Substances:

Year:  2012        PMID: 23350353

Source DB:  PubMed          Journal:  J Exp Ther Oncol        ISSN: 1359-4117


  1 in total

1.  Embryonal rhabdomyosarcoma of the cervix presenting as a cervical polyp in a 16-year-old adolescent: a case report.

Authors:  Sofia Jayi; Hakima Bouguern; Fatima Zohra Fdili; Hikmat Chaara; Leila Chbani; Imane Hafidi; Imane Kamaoui; Samia Arifi; Naoufal Mellas; Touria Bouhafa; Khalid Hassouni; Siham Tizniti; Afaf Laamarti; My Abdelilah Melhouf
Journal:  J Med Case Rep       Date:  2014-07-01
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.