Literature DB >> 23348648

Analysis of adhesions resulted from mesh fixation with fibrin sealant and suture: experimental intraperitoneal model.

Juliano Hermes Maeso Montes1, André Vicente Bigolin, Renata Baú, Roberto Nicola, João Vicente Machado Grossi, Cláudia Juliana Loureiro, Leandro Totti Cavazzola.   

Abstract

OBJECTIVE: To compare surgical fixation of polypropylene mesh (PP) and coated polypropylene mesh (PCD) using polypropylene suture and fibrin glue, as for the formation of intraperitoneal adhesions.
METHODS: A sample of 46 female Wistar rats were randomized into six groups: two control groups, with five rats each, were subjected to one medial incision (MI) and the other to a U-shaped incision (UI), none of these groups received the mesh. Two groups of PP mesh, with ten rats, fixed with suture (PPF), the other with six rats, fixed with biological glue (PPC). And two groups of PCD mesh, at first, with ten animals, the mesh was fixed with sutures (PCDFs) and the second with ten animals with biological glue (PCDC).
RESULTS: After 21 days, the control groups showed no significant adhesions. The PPC group showed a lower degree of adhesion than the PPF group (p = 0.01). There was no difference between the groups with PCD.
CONCLUSION: Comparison of fixation was statistically different only with PP mesh, with lesser degrees of adherence when using the glue. Adhesions were predominantly located at the extremities of the meshes studied.

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Year:  2012        PMID: 23348648     DOI: 10.1590/s0100-69912012000600011

Source DB:  PubMed          Journal:  Rev Col Bras Cir        ISSN: 0100-6991


  3 in total

1.  THE USE OF SURGICAL ADHESIVE AND SUTURE FIXING MESHES TO THE ABDOMINAL WALL: AN EXPERIMENTAL STUDY IN RATS.

Authors:  Carlos Alberto Lima Utrabo; Cesar Roberto Busato; Mário Rodrigues Montemór-Netto; Leandro Cavalcanti Lipinski; Vitória Rossetim Celinski; Mylena Fernanda Ferronato; Osvaldo Malafaia; Adriana Yuriko Koga
Journal:  Arq Bras Cir Dig       Date:  2022-06-17

Review 2.  Fibrin Sealant: The Only Approved Hemostat, Sealant, and Adhesive-a Laboratory and Clinical Perspective.

Authors:  William D Spotnitz
Journal:  ISRN Surg       Date:  2014-03-04

3.  Critical analysis of experimental model for study of adhesions after incisional hernias induced in rats' and repair of abdominal wall with different biomaterials.

Authors:  Leonardo Carvalho Serigiolle; Renato Lamounier Barbieri; Helbert Minuncio Pereira Gomes; Daren Athiê Boy Rodrigues; Sarah do Valle Studart; Pedro Luiz Squilacci Leme
Journal:  Arq Bras Cir Dig       Date:  2015 Jul-Sep
  3 in total

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